Publications by authors named "Gunes Ozen-Eroglu"

Article Synopsis
  • * The complexes were analyzed and characterized through various techniques, including single-crystal X-ray diffraction, revealing a distorted square planar geometry with specific ligand interactions.
  • * Cytotoxicity tests showed that the chloro-complex exhibited greater effectiveness against a leukemia cell line compared to the chemotherapy drug cisplatin, while being less toxic to healthy cells.
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Background: 1,25(OH)2D3(Calcitriol), which is a broad regulatory molecule, plays a role in changing the efficacy of chemotherapeutic drugs. Cisplatin is one of a current standard chemotherapy regimen for bladder cancer. Increasing the effectiveness of the treatment and reducing the side effects to chemotherapeutics are of great importance in bladder cancer.

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Purpose: The effects of four different self-adhesive resin cement materials on cell viability and apoptosis after direct and indirect exposure were evaluated using different cell culture techniques.

Materials And Methods: Self-adhesive cements were applied to NIH/3T3 mouse fibroblasts by the extract test method, cell culture inserts, and dentin barrier test method. After exposure periods of 24 h and 72 h, the cytotoxicity of these self-adhesive materials was evaluated using the MTT assay (viability) and the Annexin-V-FITC/PI staining (apoptosis).

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