Publications by authors named "Gunes H"

The aim of this study is to examine the outcomes of superiorly placed monocortical single miniplate fixation in the treatment of mandibular angle fractures and evaluate treatment efficacy through craniometric measurements. Postoperative craniometrics were compared with both the preoperative measurements and the control group. Thirty-four patients were included with a mean follow-up of 3.

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  • - Mushrooms are nutritious with high protein and healthy fats, and they are being researched for their health benefits and potential industrial applications, particularly their natural compounds.
  • - The study explored the cytotoxic effects of different extracts from the mushroom on various cancer cell lines using various scientific assays, finding that the hexane extract was most effective against A549 cells, while methanol extract showed considerable efficacy against PC-3 cells.
  • - Additionally, the methanol extract exhibited strong antioxidant activity and reduced inflammatory markers (like TNF-α and VEGF), while the hexane extract displayed notable antimicrobial properties against several pathogens.
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  • * The study focused on the relationship between two genetic variations in the MTHFR gene, C677T and A1298C, and osteoporosis among Turkish postmenopausal women, analyzing DNA from 200 volunteers.
  • * Results indicated that while the A1298C polymorphism is statistically linked to osteoporosis, the C677T variant showed no significant connection; further research is needed with larger samples to explore genetics and environmental influences on osteoporosis.
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This study aimed to investigate anxiety, depression levels, and emotional/behavioral problems of children and adolescents while being treated in the COVID-19 unit. The present study included 50 children who were COVID-19 positive, aged 7-18 years, and 50 age- and gender-matched healthy controls. The sociodemographic data form and Revised Child Anxiety and Depression Scale-Child Version (RCADS-C) were applied to all children, and all families were asked sociodemographic data form, Revised Child Anxiety and Depression Scale-Parent Version (RCADS-P), and Strengths and Difficulties Questionnaire (SDQ).

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Aim Of The Study: Non-thyroidal illness syndrome (NTIS) is often observed in critically ill patients. This study aimed to examine thyroid hormone changes in patients with chronic obstructive pulmonary disease (COPD) experiencing acute hypercapnic respiratory failure (AHRF) and to evaluate the impact of these alterations on clinical outcomes.

Materials And Methods: This retrospective investigation involved 80 COPD patients (age 71.

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Purpose: Scleroderma is a multisystemic disorder characterised by inflammatory and vascular anomalies, and excess fibrosis. Progressive systemic sclerosis (PSS) mainly progresses with skin, joint, lung, heart, and kidney involvement. Involvement of cerebral vessels is rare in both localised scleroderma and PSS.

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  • * Results showed that stages of hepatic encephalopathy improved over time post-surgery, with most severe cases occurring within the first 6 months post-transplant.
  • * Although there was a regression in symptoms, complete recovery was not achieved, indicating a need for additional treatment approaches beyond transplantation.
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Paraneoplastic neurological syndromes occur due to immune-mediated neuronal dysfunction secondary to systemic malignancy, and symptoms can usually be seen before malignancy. There are many subtypes that depend on the antibodies present or the proteins they target. Accurate epidemiological data are lacking as it is difficult to diagnose.

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Circadian rhythms synchronize all biological functions, enabling humans to foresee and respond better to periodic environmental changes. The coronavirus disease (COVID-19) lockdown regulations significantly changed the lighting conditions in pregnant women, leading to chronological disruption. This study aimed to investigate the impact of the COVID-19 on the circadian rhythm of cesarean deliveries.

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Background: Preoperative left ventricular (LV) ejection fraction (PreLVEF) and preoperative LV end-systolic diameter (PreESD) are known predictors for postoperative LV dysfunction after mitral valve repair (MVR). Fragmented QRS (fQRS) evaluated in 12-derivation electrocardiography has widely been accepted as a sign of myocardial fibrosis. In the present study, we aimed to evaluate the relationship between fQRS in preoperative 12‑lead electrocardiography (ECG) and postoperative LV dysfunction that develop after MVR in patients with severe primary mitral regurgitation (MR) due to mitral valve prolapse (MVP).

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Soluble guanylate cyclase (sGC) modulation has been scrutinized in several disease states including heart failure (HF). Recently, it was shown that an sGC modulator improved HF-related hospitalization significantly, though, there was no benefit related to mortality. Herein, a comprehensive meta-analysis of randomized controlled trials (RCTs) for sGC modulation in HF patients was provided in agreement with the PRISMA statement.

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Malignant pleural mesothelioma (MPM) is a rare type of cancer, and its main risk factor is exposure to asbestos. Accordingly, our knowledge of the genomic structure of an MPM tumor is limited when compared to other cancers. In this study, we aimed to characterize complex genomic rearrangement patterns and variations to better understand the genomics of MPM tumors.

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This study analyzed data collected on a slaughterhouse from 2017 to 2021, belonging to five hundred and twenty one Anatolian water buffalos from different farms located in Edirne, Istanbul, and Kirklareli. Specifically, it aimed to determine the factors affecting the carcass weights and slaughter ages of the Anatolian water buffalos. The results of the study showed that the slaughter age of the buffalos was a significant determinant of their carcass weights.

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Background: The association of soluble suppression of tumorigenesis-2 (sST2) levels with prognosis in pulmonary embolism (PE) is unknown.

Objective: This study aimed to investigate the relationship between sST2 levels in patients with acute PE and 6-month mortality and recurrent hospitalizations.

Methods: This prospective study included 100 patients with acute PE.

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Idiopathic hypertrophic pachymeningitis is a rare, fibrosing inflammatory disease that causes localized or diffuse thickening of the dura mater in the brain and/or spinal cord. It may be cranial, spinal, and/or craniospinal pachymeningitis depending on the place of involvement. In our case, a 34-year-old woman presented with sixth cranial nerve involvement and headache and was diagnosed with idiopathic hypertrophic pachymeningitis as a result of the exclusion of other causes and central nervous system imaging.

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Tumefactive multiple sclerosis (MS) is a subtype of atypical and rare MS that presents with tumor-like lesions in the central nervous system. The lesions may demonstrate a mass effect, edema, with ring enhancement. They can be mistaken for brain tumors or brain abscesses radiologically and clinically.

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Objective: The aim of this study was to analyze the effects of mindfulness-based cognitive therapy on the adherence of liver transplant recipients to immunosuppressive therapy with a randomized controlled design.

Method: This randomized controlled trial was performed with 120 liver transplant recipients hospitalized at the liver transplant department of a research and practice hospital (n = 120). While we administered no intervention to the patients in the control group (n = 60), we provided Mindfulness-Based Cognitive Therapy to those in the experimental group (n = 60).

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Background: This study was designed to examine the effect of guided imagery applied to geriatric orthopaedic patients on preoperative anxiety and comfort.

Methods: This study was conducted as a randomized controlled trial. The population of the study consisted of geriatric patients treated in the orthopaedics and traumatology clinic of a university hospital.

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  • - The study investigates the presence of axonal spheroids in motor axons and C-fibers of patients with amyotrophic lateral sclerosis (ALS) using corneal confocal microscopy and skin biopsies.
  • - It involved 31 ALS patients and 20 healthy subjects, measuring various nerve fiber metrics and dendritic cell density, revealing that ALS patients had more axonal spheroids and higher dendritic cell density compared to controls.
  • - The findings suggest that analyzing dendritic cells and axonal structures in ALS patients may help understand the disease's mechanisms and identify potential biomarkers for diagnosis or monitoring.
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Behcet's disease; it is a vascular-inflammatory chronic recurrent disease that can affect many systems in the body. Millard Gubler syndrome is one of the brainstem syndromes that occurs due to lesions involving the ventral part of the caudal pons. We wanted to present a case of Millard Gubler syndrome, which developed due to Behçet's syndrome lesion in the pons ventral region in a patient who presented with limitation of outward gaze on the left, inability to close the left eye completely, inability to completely wrinkle the left side of the forehead, and loss of contralateral muscle strength.

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This randomized-controlled trial aimed to investigate the effect of bed exercises on postoperative anxiety, pain, early ambulation and mobilization. This study was conducted with a randomized-controlled trial design and in the general surgical clinic of a research and training hospital. A total of 120 patients (60 in the experimental group and 60 in the control group) scheduled for major abdominal surgery took part in the study.

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Malignant pleural mesothelioma (MPM) is rare and aggressive cancer. The most important risk factor for MPM is exposure to asbestos. In this study, we scanned the genomes of individuals MPM and asbestos-induced chronic pleuritis (AICP) to compare and determine copy number alterations (CNAs) between two asbestos-related diseases.

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Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease characterized by right heart failure following recurrent pulmonary embolism (PE). It is important to know the predictors of the development of CTEPH after PE as it is a treatable cause of pulmonary arterial hypertension. Soluble ST2 is a biomarker closely associated with heart failure and the inflammatory process.

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Studies conducted in recent years have indicated a relationship between epilepsy and gut microbiota. Ion channels, excitatory/inhibitory balance and regulatory systems play a role in the pathophysiology of epilepsy. In addition, gut dysbiosis is also involved in the pathophysiology of epilepsy.

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