Scalable Solution Phase Synthesis of 2D Siloxene a Two-Step Interlayer Expansion Process.

Two-dimensional (2D) siloxene is attracting considerable research interest recently principally owing to its inherent compatibility with silicon-based semiconductor technology. -The synthesis of siloxene has been mostly limited to multilayered structures using traditional topochemical reaction procedures. Herein, we report high-yield synthesis of single to few-layer siloxene nanosheets by developing a two-step interlayer expansion and subsequent liquid phase exfoliation procedure.

Correlating Nanoscale Structures with Electrochemical Properties of Solid Electrolyte Interphases in Solid-State Battery Electrodes.

Here, we investigate the nonlinear relationship between the content of solid electrolytes in composite electrodes and the irreversible capacity via the degree of nanoscale uniformity of the surface morphology and chemical composition of the solid electrolyte interphase (SEI) layer. Using electrochemical strain microscopy (ESM) and X-ray photoelectron spectroscopy (XPS), changes of the chemical composition and morphology (Li and F distribution) in SEI layers on the electrodes as a function of solid electrolyte contents are analyzed. As a result, we find that the solid electrolyte content affects the variation of the SEI layer thickness and chemical distributions of Li and F ions in the SEI layer, which, in turn, influence the Coulombic efficiency.

Structural finite element model updating considering soil-structure interaction using ls-dyna in loop.

In this study, a finite element model updating method which can consider soil-structure interaction was developed to analyze the effect of soil properties on the structural response while considering interaction between the soil and the structure. Additionally, LS-DYNA, a commercial finite element program, was included in the loop of the proposed technique using MATLAB to conveniently utilize the complex structures updated by the model. To validate the performance of the proposed method, a large-scale shake table test was conducted.

A Scalp Scar-Reducing Procedure for the Hair Transplant Donor Area Using a Columnar Trichophytic Suture: A Case Report.

Background: One of the main concerns of patients who undergo hair transplantation surgery such as follicular unit strip surgery is scar widening on surgical sites. Until now, trichophytic suture, double-layer suture, tattoos, follicular unit transplantation on scars are suggested as a solution.

Case Report: A 23-year-old man with frontal hair loss underwent follicular unit strip surgery.

Smart glasses and telehealth services by professionals in isolated areas in Korea: Acceptability and concerns.

Background: Smart glass technology offers remote interaction between health professionals for telehealth, alleviating healthcare disparities in isolated areas.

Objective: To evaluate the professionals' perceptions of smart glass technology as a tool for telehealth and distance learning.

Method: This mixed-method study on health professionals in 10 different island areas in Korea involved participants experiencing a smart glass-based telehealth system using the scenario of clinical consultation with remote specialists.

Statistical discrimination using different machine learning models reveals dissimilar key compounds of soybean leaves in targeted polyphenol-metric metabolomics in terms of traits and cultivation.

Soybean (SB) leaves (SLs) contain diverse flavonoids with health-promoting properties. To investigate the chemical constituents of SB and their correlations across phenotypes, growing periods, and environmental factors, a validated separation method for mass detection was used with targeted metabolomics. Thirty-six polyphenols (1 coumestrol, 5 flavones, 18 flavonols, and 12 isoflavones) were identified in SLs, 31 of which were quantified.

Nanoscale Visualization of the Electron Conduction Channel in the SiO/Graphite Composite Anode.

Conductive atomic force microscopy (C-AFM) is widely used to determine the electronic conductivity of a sample surface with nanoscale spatial resolution. However, the origin of possible artifacts has not been widely researched, hindering the accurate and reliable interpretation of C-AFM imaging results. Herein, artifact-free C-AFM is used to observe the electron conduction channels in Si-based composite anodes.

Geometrical Influence on Particle Transport in Cross-Flow Ultrafiltration: Cylindrical and Flat Sheet Membranes.

Cross-flow membrane ultrafiltration (UF) is used for the enrichment and purification of small colloidal particles and proteins. We explore the influence of different membrane geometries on the particle transport in, and the efficiency of, inside-out cross-flow UF. For this purpose, we generalize the accurate and numerically efficient modified boundary layer approximation (mBLA) method, developed in recent work by us for a hollow cylindrical membrane, to parallel flat sheet geometries with one or two solvent-permeable membrane sheets.

Risk factors for deep vein thrombosis even using low-molecular-weight heparin after total knee arthroplasty.

Background: With an increase in deep vein thrombosis (DVT) following total knee arthroplasty (TKA) in the Asian population, most surgeons today use a form of prophylactic anticoagulant agents in patients after TKA. Nevertheless, DVT occasionally develops even in these patients with prophylaxis. The purpose of this study was to identify the risk factors for DVT after TKA in cases of postoperative low-molecular-weight heparin (LMWH) use.

Fluoroquinolone and no risk of Achilles-tendinopathy in childhood pneumonia under eight years of age-a nationwide retrospective cohort.

Background: The emergence of macrolide-resistant Mycoplasma pneumoniae pneumonia (MRMP) has made its treatment challenging. A few guidelines have recommended fluoroquinolones (FQs) as second-line drugs of choice for treating MRMP in children under the age of eight, but concerns about potential adverse events (i.e.

Ultrasound-guided needle decompression and steroid injection for calcific tendinitis of the shoulder: risk factors for repeat procedures and outcome analysis.

Background: Although ultrasound-guided needle decompression (US-GND) can treat calcific tendinitis of the shoulder effectively, repeat procedures might be required for unresolved symptoms. We evaluated the overall clinical outcomes of US-GND with subacromial steroid injection and the final results and factors predisposing toward repeat procedures.

Methods: Ninety-eight patients who underwent US-GND for calcific tendinitis of the supraspinatus/infraspinatus were analyzed between March 2017 and December 2018.

Reducing Time to Discovery: Materials and Molecular Modeling, Imaging, Informatics, and Integration.

Multiscale and multimodal imaging of material structures and properties provides solid ground on which materials theory and design can flourish. Recently, KAIST announced 10 flagship research fields, which include KAIST Materials Revolution: Materials and Molecular Modeling, Imaging, Informatics and Integration (M3I3). The M3I3 initiative aims to reduce the time for the discovery, design and development of materials based on elucidating multiscale processing-structure-property relationship and materials hierarchy, which are to be quantified and understood through a combination of machine learning and scientific insights.

Development of a voiding diary using urination recognition technology in mobile environment.

We invented a wearable device that can measure voiding time and frequency by checking a habitual series of characteristic motions among men. This study collected and analyzed urination time data collected smart bands worn by patients to resolve the clinical issues posed by using voiding charts. By developing a smart band-based algorithm for assessing urination time in patients, this study aimed to explore the feasibility of urination management systems.

Modeling cross-flow ultrafiltration of permeable particle dispersions.

Cross-flow ultrafiltration is a pressure-driven separation and enrichment process of small colloidal particles where a colloidal feed dispersion is continuously pumped through a membrane pipe permeable to the solvent only. We present a semi-analytic modified boundary layer approximation (mBLA) method for calculating the inhomogeneous concentration-polarization (CP) layer of particles near the membrane and the dispersion flow in a cross-flow filtration setup with a hollow fiber membrane. Conditions are established for which unwarranted axial flow and permeate flow reversal are excluded, and non-monotonic CP profiles are observed.

Nanoscale effects of beverages on enamel surface of human teeth: An atomic force microscopy study.

Dental erosion has become a prevalence disease and attracted increasing attention worldwide. In this research, we quantitatively evaluate the mechanical and morphological changes in the very early stages of softening and weakening of human enamel surfaces induced by soft drinks using atomic force microscopy (AFM). With an increase of the immersion time in soft drinks, we found a significant increase of surface roughness (R) of the enamel surface.

Selective Identification of α-Galactosyl Epitopes in -Glycoproteins Using Characteristic Fragment Ions from Higher-Energy Collisional Dissociation.

The α-galactosyl epitope is a terminal -glycan moiety of glycoproteins found in mammals except in humans, and thus, it is recognized as an antigen that provokes an immunogenic response in humans. Accordingly, it is necessary to analyze the α-galactosyl structure in biopharmaceuticals or organ transplants. Due to an identical glycan composition and molecular mass between α-galactosyl -glycans and hybrid/high-mannose-type -glycans, it is challenging to characterize α-galactosyl epitopes in -glycoproteins using mass spectrometry.

Computational classification of core and outer fucosylation of N-glycoproteins in human plasma using collision-induced dissociation in mass spectrometry.

Rationale: Glycoprotein fucosylation, one of the major posttranslational modifications, is known to be highly involved in proteins related to various cancers. Fucosylation occurs in the core and/or outer sites of N-glycopeptides. Elucidation of the fucosylation type of N-glycoproteins is therefore important.

Classification of Mucin-Type -Glycopeptides Using Higher-Energy Collisional Dissociation in Mass Spectrometry.

Changes in mucin-type -glycosylation of human proteins affect protein function, immune response, and cancer progression. Since -glycoproteins are characterized by the microheterogeneity of diverse -glycans with no conserved sequence and the macroheterogeneity of multiple glycosylation sites on serine and/or threonine in human proteins, the assessment of different mucin types, such as Tn-antigen, core 1, and core 2, and their extended core types in -glycopeptides, is extremely challenging. Here, we present an (-GPA) that automatically classifies mucin-type -glycosylation using higher-energy collisional dissociation (HCD) in mass spectrometry.

BMDMS-NP: A comprehensive ESI-MS/MS spectral library of natural compounds.

The Bioinformatics & Molecular Design Research Center Mass Spectral Library - Natural Products (BMDMS-NP) is a library containing the mass spectra of natural compounds, especially plant specialized metabolites. At present, the library contains the electrospray ionization tandem mass spectrometry (ESI-MS/MS) spectra of 2739 plant metabolites that are commercially available. The contents of the library were made comprehensive by incorporating data generated under various experimental conditions for compounds with diverse molecular structures.

Biportal endoscopic discectomy for high-grade migrated lumbar disc herniation.

Objective: Although endoscopic procedures for lumbar disc herniation have improved greatly and offer many advantages, the indications are limited mostly to nonmigrated or low-grade migrated disc herniation. Endoscopic application in migrated disc herniation cases is still challenging and technically demanding. The goal in this study was to determine the feasibility of biportal endoscopic discectomy for removal of high-grade migrated disc herniation.

Author Correction: Machine Learning Classifies Core and Outer Fucosylation of N-Glycoproteins Using Mass Spectrometry.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Machine Learning Classifies Core and Outer Fucosylation of N-Glycoproteins Using Mass Spectrometry.

Protein glycosylation is known to be involved in biological progresses such as cell recognition, growth, differentiation, and apoptosis. Fucosylation of glycoproteins plays an important role for structural stability and function of N-linked glycoproteins. Although many of biological and clinical studies of protein fucosylation by fucosyltransferases has been reported, structural classification of fucosylated N-glycoproteins such as core or outer isoforms remains a challenge.