Polidocanol injection for chemical delay and its effect on the survival of rat dorsal skin flaps.

Background And Aim: Surgical delay is an invasive method requiring a two-stage surgical procedure. Hence, methods that may serve as an alternative to surgical delay have become the focus of interest of research studies. From a conceptual view, any technique that interrupts the blood flow along the edges of a proposed flap will render the flap ischemic and induce a delay phenomenon.

[Repair of soft tissue defects of the nose].

Objectives: Soft tissue defects of the nose resulting from lesions may cause aesthetic and functional problems if they are not properly repaired.

Patients And Methods: In this study, a retrospective analysis was conducted of 104 patients (59 females, 45 males; mean age 53 years; range 33 to 89 years) who were operated in our clinic between November 2005 and July 2009. Nasal soft tissue defects resulting from excision were closed with a primer closure for 16 patients, a procerius muscle skin flap for 11 patients, a nasolabial flap for 26 patients, a dorsal nasal flap for 12 patients, a forehead flap for three patients, an orbicularis oculi muscle skin flap for three patients, a V-Y advancement flap for seven patients, a bilateral V-Y advancement flap for one patient, a Banner flap for nine patients, a bilobe flap for eight patients, an interpolation flap for two patients, a skin graft for 10 patients.

A case of cellulitis causing tissue defect during etanercept therapy.

Tumor necrosis factor-alpha (TNF-α) antagonists are employed increasingly during recent years in patients with active rheumatoid arthritis who do not respond to disease-modifying anti-rheumatic drugs. Contraindications such as infections, auto-antibody formation and hypersensitive reactions can be observed during the treatment with TNF-α antagonist drugs. Our case was a 52-year-old woman, followed by several centers for a period of 21 years with a seropositive, erosive and nodular RA diagnosis.

Cartilage Z plasty on lateral crus for treatment of alar cartilage malposition.

Background: Alar cartilage malposition is an anatomical variation. Axis of the lateral crus lies cephalically and can be parallel to the cephalic septum. The characterised findings of the malposition are broad and bulbous nasal tip, abnormal lateral crural axes, long alar creases that extend to the nostril rims, alar wall hollows, frequent nostril deformities and associated external valvular incompetence.

Expansion of surviving skin paddle of neurocutaneous island flaps in rats by VEGF.

The purpose of this study was to investigate whether vascular endothelial growth factor (VEGF) can enlarge the skin paddles of neurocutaneous flaps in rats. Wistar albino rats were used in four groups: Group 1, (n = 10): neurocutaneous island flap; Group 2, (n = 10): neurocutaneous island flap, surgical delay; Group 3, (n = 10): neurocutaneous island flap, VEGF; Group 4, (n = 10): graft. A 3 x 3-cm, neurocutaneous island flap was elevated on the anterolateral skin of the thigh of the rats.