GPU-accelerated and pipelined methylation calling.

Motivation: The third-generation DNA sequencing technologies, such as Nanopore Sequencing, can operate at very high speeds and produce longer reads, which in turn results in a challenge for the computational analysis of such massive data. is a software package for signal-level analysis of Oxford Nanopore sequencing data. Call-methylation module of can detect methylation based on Hidden Markov Model (HMM).