Sperm RNA quantity and PRM1, PRM2 , and TH2B transcript levels reflect sperm characteristics and early embryonic development.

Spermatozoa have a highly complex RNA profile. Several of these transcripts are suggested as biomarkers for male infertility and contribute to early development. To analyze the differences between sperm RNA quantity and expression of protamine ( PRM1 and PRM2 ) and testis-specific histone 2B ( TH2B ) genes, spermatozoa from 33 patients who enrolled in assisted reproduction treatment (ART) program were analyzed.

Mystery of idiopathic male infertility: is oxidative stress an actual risk?

Objective: To study the role of oxidative stress in sperm dysfunction in Turkish idiopathic infertile men.

Design: Prospective study.

Setting: Medical laboratory.

The role of heat shock protein 70 (Hsp 70) in male infertility: is it a line of defense against sperm DNA fragmentation?

Objective: To clarify the role of heat shock protein 70 (Hsp 70) and its relation with DNA damage in male infertility.

Design: Prospective study.

Setting: Andrology laboratory of Istanbul Medical Faculty.