Publications by authors named "Gulkesen K"

Background: It was estimated that there were 537 million people with diabetes mellitus in 2021, representing 10.5% of the global adult population. Diabetes prevalence in Turkey is 13.

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We aimed to observe the effects of a self-management mobile app for patients with schizophrenia. A mobile app was designed to record and remind users to take medication and some daily activities. The patients were asked to use the app for one month.

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A well-known effect size (ES) indicator is Cohen's d. Cohen defined d measures of small, medium, and large ES as 0.2, 0.

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Background: Many countries adopt eHealth applications to support patient-centered care. Through information exchange, these eHealth applications may overcome institutional data silos and support holistic and ubiquitous (regional or national) information logistics. Available eHealth indicators mostly describe usage and acceptance of eHealth in a country.

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Introduction Nowadays, the expectations for functional prostatectomy outcomes are quite high. Robot-assisted laparoscopic radical prostatectomy (RALRP) has become an increasingly common treatment option for men with localized prostate cancer. In this study, we aimed to present the results of our bilateral nerve-sparing RALRP procedure and to evaluate the effects of the learning curve (LC) on perioperative data, early oncologic, and functional outcomes.

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Background: Platelet-rich plasma (PRP) treatment for androgenetic alopecia (AGA) has been increasingly used, yet there remains a dearth of data on the effectiveness of this approach.

Aim: To compare the efficacy and safety of physically activated PRP injections vs placebo in the treatment of male AGA.

Methods: Twenty-five healthy male patients with AGA were enrolled in a randomized, placebo-controlled, crossover study with the treatments of PRP and placebo.

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Objectives: To identify major research subjects and trends in medical informatics research based on the current set of core medical informatics journals.

Methods: Analyzing journals in the Web of Science (WoS) medical informatics category together with related categories from the years 2013 to 2017 by using a smart local moving algorithm as a clustering method for identifying the core set of journals. Text mining analysis with binary counting of abstracts from these journals published in the years 2006 to 2017 for identifying major research subjects.

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Background: Recognizing facial expressions is an important social skill. In some psychological disorders such as schizophrenia, loss of this skill may complicate the patient's daily life. Prior research has shown that information technology may help to develop facial expression recognition skills through educational software and games.

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Objective: To evaluate a system we developed that connects natural language processing (NLP) for information extraction from narrative text mammography reports with a Bayesian network for decision-support about breast cancer diagnosis. The ultimate goal of this system is to provide decision support as part of the workflow of producing the radiology report.

Materials And Methods: We built a system that uses an NLP information extraction system (which extract BI-RADS descriptors and clinical information from mammography reports) to provide the necessary inputs to a Bayesian network (BN) decision support system (DSS) that estimates lesion malignancy from BI-RADS descriptors.

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In some psychological disorders such as autism and schizophrenia, loss of facial expression recognition skill may complicate patient's daily life. Information technology may help to develop facial expression recognition skill by educational software and games. We designed and developed an interactive web-based educational program with which we performed a usability study before investigating its effectiveness on the schizophrenia patients' ability of emotion perception.

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Social network analysis is a well-known method for discovering the social complexities of relationships. In this paper, we present the results of its application in a healthcare environment, i.e.

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The purpose of this study is to investigate the potential protective effect of the flavonoid Luteolin on ischemia-reperfusion (IR) injury in mouse intestine, which has not previously been studied. Twenty-four female C57BL/6 mice were randomly assigned to four groups, each consisting of 6 mice: a sham group (laparotomy, but no IR injury), a sham + Luteolin group (no IR, and Luteolin was administered intraperitoneally 30 min after laparotomy), IR group (30 min occlusion of the superior mesenteric artery (SMA) then 2 hr' reperfusion), IR + Luteolin (30 min occlusion of the SMA then 2 hr' reperfusion; Luteolin was administered intraperitoneally before reperfusion). Intestine tissues were harvested from the mice for histopathological and biochemical analysis.

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Our study indicated the relationship between tumor length and clinicopathologic characteristics as well as long-term survival in esophageal cancer. A total of 116 patients who underwent curative surgery for thoracic esophageal cancer with standard lymphadenectomy in 2 fields between 2000 and 2010 were included in the study. The medical records of these patients were retrospectively reviewed.

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Inter and intra-observer variability in mammographic interpretation is a challenging problem, and decision support systems (DSS) may be helpful to reduce variation in practice. Since radiology reports are created as unstructured text reports, Natural language processing (NLP) techniques are needed to extract structured information from reports in order to provide the inputs to DSS. Before creating NLP systems, producing high quality annotated data set is essential.

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Recently, numerous systems for geo-tracking Alzheimer's patients with dementia have been developed and reported to be functional for the purposes of security and data collection. However, studies stated possible loss of freedom and autonomy for patients, along with violations of their privacy, which may lead to loss of prestige/dignity. In this study, a geotracking system that aims to balance patients' security and their need for privacy and autonomy is proposed.

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'Personal Nutrition Management Tool' (PENUMAT) is an interactive web-based application which aims to help individuals seeking nutrition information on the Internet. However, little is known about the usability of such applications. The purpose of this study was to evaluate the usability of PENUMAT using multi-method approach.

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Purpose: Several concepts to improve the diagnostic accuracy of prostate specific antigen (PSA) for prediction of prostate cancer have been studied. The aim of this study was to examine and compare the methods used for improving the diagnostic accuracy of PSA in a country with low incidence of prostate cancer.

Methods: 997 patients with prostate biopsy were included into study.

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Background: Some image compression methods are used to reduce the disc space needed for the image to store and transmit the image efficiently. JPEG is the most frequently used algorithm of compression in medical systems. JPEG compression can be performed at various qualities.

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Background: Flap operations are frequently performed in diabetic patients. Nevertheless, we could find no experimental study examining diabetes mellitus's effect on the flaps' survival. For this reason, we designed this study as a random-pattern skin-flap model of diabetic rats in 1999.

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In the last years, a lot of health portals have emerged which give service to health professionals. Neither number nor usage patterns of these portals have been well known. In this study, we analysed the usage patterns of a Turkish health portal.

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The objective of this study was to investigate mast cells and iNOS expression in testis tissue, and to correlate these results with spermatogenic disorders. A total of 136 testicular biopsies were obtained from the testes of 80 patients with infertility. Their age ranged from 21 to 45 years.

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Objective: The purpose of the study was to determine if the tumor suppressor gene phosphate and tensin homolog (PTEN) (mutated in multiple advanced cancers 1) in combination with Gleason scoring and serum prostate specific antigen (PSA) could be employed to better predict the progression of prostate carcinoma.

Materials And Methods: The study group consisted of 43 patients with benign prostate hyperplasia (BPH), 15 with organ confined prostate carcinoma (OCPCa), and 18 with advanced prostate carcinoma (APCa). Prostate tissue samples were obtained from radical prostatectomy, transurethral resection, and TRUS guided trans-rectal needle biopsy and then evaluated for biomarker expression.

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The tolerability and efficacy of the continuous infusion of cisplatin during radiotherapy was studied by tumour response, survival and pelvic control, in carcinoma of the cervix. 44 patients with stage IIB-IIIB cervical carcinoma were prospectively randomized into two groups: radiation alone (control group) versus radiation plus cisplatin (study group). While there was no significant difference in diarrhoea and urinary complication scores, emesis and appetite changes were significantly greater in the study group.

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Purpose: Erectile dysfunction (ED) occurs in 20% to 54% of men with Peyronie's disease (PD). We investigated the role of vascular status in the pathophysiology of ED in patients with PD.

Materials And Methods: A total of 509 consecutive men with PD (group 1--impotent 259, 1a, and potent 250, 1b, mean age +/- SD 54.

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