Publications by authors named "Gulin Alkan"
Objective: Extrapulmonary neuroendocrine carcinoma (EP-NEC) is a rare tumor type, and a standard therapy for EP-NEC has not yet been established. The purpose of this research was to explore the overall survival (OS) and therapeutic effects of platinum-etoposide combination therapy in EP-NEC.
Methods: This retrospective study was conducted based on the medical records from January 2010 to March 2020.
Majority of patients with breast cancer were diagnosed with locally advanced stages of the disease (54%). This study aimed to explain the pathological response received to neoadjuvant chemotherapy (NACT) according to the molecular classification of breast cancer in patients with locally advanced tumors. One hundred and one patients with locally advanced breast cancer treated with neoadjuvant chemotherapy were analyzed.
View Article and Find Full Text PDFIntroduction: Bevacizumab, a monoclonal antibody against the vascular endothelial growth factor receptor, is the standard treatment of recurrent glioblastoma multiforme. In addition to common systemic side effects of bevacizumab, there are rare cases of cranial nerve palsy.
Case Report: We report a case of transient oculomotor nerve palsy after systemic administration of bevacizumab.
Undoubtedly, cancer patients have suffered the most from the COVID-19 pandemic process. However, cancer is a heterogeneous disease, and each patient has responded differently to COVID-19. We aimed to describe the clinical characteristics and outcomes of patients with cancer and COVID-19.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess the mortality rates of cancer patients hospitalized with COVID-19 and identify clinical and demographic factors affecting those rates.
- Out of 2401 COVID-19 patients, 92 cancer patients were analyzed, revealing a significantly higher mortality rate of 23.9% compared to 6.2% in the general COVID-19 population, with those having metastasis experiencing even higher rates.
- Key factors influencing mortality included smoking status, and elevated levels of CRP, ferritin, LDH, and D-dimer, as well as lower levels of albumin and hemoglobin, indicating a need for more extensive research on these prognostic markers.
A rare complication in a patient taking rivaroxaban: Alveolar hemorrhage.
Turk Kardiyol Dern Ars
January 2018
Alveolar hemorrhage (AH) is a heterogeneous clinical syndrome with a high mortality rate that is characterized by extensive bleeding into the alveolar spaces. AH usually develops secondary to immunological disease and, less frequently, to drug use. Presently described is the case of an 86-year-old woman with AH who had been using rivaroxaban for 6 months.
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