Publications by authors named "Guleer Shahab"
Ischemic stroke is a leading cause of morbidity and mortality. We have previously shown that deletion of endothelial cell (EC) Panx1 reduces ischemic stroke infarct volume and reduces cerebral arterial myogenic reactivity, which regulates cerebral blood flow. We hypothesized that EC Panx1 content dictates ischemic stroke outcome and thus increased EC Panx1 expression will worsen ischemic stroke outcomes due to exacerbated myogenic tone development and impaired cerebral blood flow recovery.
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- * The study developed a tailored mobile health intervention based on formative research, input from a community advisory board of Black men, and survey data to enhance CRC screening rates.
- * Key findings included the necessity for private and accessible delivery methods, including the involvement of local health clinics due to significant mistrust of healthcare systems and information gaps among the target population.
Introduction: The study aimed to investigate the positivity rate of anti-SARS-CoV-2 antibodies and associated factors.
Methodology: Data and blood samples were collected between January 10th and December 30th, 2021 based on COVID-19 infection by using a designated questionnaire. The blood samples were used for the detection of total SARS-CoV-2 antibodies.
Background: Replacement therapies have revolutionized treatment paradigms in metabolic diseases by restoring defective enzymes and supplementing missing downstream metabolites. Through most of the 20th century, no targeted therapies existed for these conditions, the only treatment options available focusing on symptoms rather than the underlying disorders. Improved understanding of the molecular pathways underlying metabolic disease has allowed not only supplementation of missing metabolites and reduction of upstream substrates, but replacement of defective or missing enzymes.
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