Publications by authors named "Gulden Eser Karlidag"
Article Synopsis
- This study analyzed 331 patients with primary brain abscesses (PBAs) from 39 centers in 16 countries, focusing on infection causes, risk factors, and mortality outcomes over a 12-year period.
- Study results showed that the majority of patients were middle-aged men (average age 46.8), with symptoms like headaches and fever; Gram-positive cocci were the most common pathogens.
- Key factors influencing mortality at 42 days included intravenous drug use and malignancy, while factors affecting 180-day mortality included temporal lobe involvement and the presence of unidentified bacteria.
Article Synopsis
- - The COVID-19 pandemic led to a rise in cases of mucormycosis, particularly in India, prompting a study to analyze factors affecting mortality in COVID-19-associated mucormycosis (CAM) among patients in mainly Asian and some African countries.
- - The study included 162 CAM patients, primarily older males, with a high prevalence of diabetes and rhino-orbital-cerebral mucormycosis; results indicated a 39% mortality rate influenced by advanced age, use of rituximab, and diabetic ketoacidosis as significant risk factors.
- - Findings suggest that surgical debridement improves survival rates, and combining antifungal treatments with surgery significantly enhances outcomes for CAM patients.
This multicentre (22 centres in Turkey) retrospective cohort study aimed to assess the clinical outcomes of patients with neutropenic fever and SARS-CoV-2 positivity. Study period was 15 March 2020-15 August 2021. A total of 170 cases (58 female, aged 59 ± 15.
View Article and Find Full Text PDFBackground: During the COVID pandemic, research has shown an increase in candidemia cases following severe COVID infection and the identification of risk factors associated with candidemia. However, there is a lack of studies that specifically explore clinical outcomes and mortality rates related to candidemia after COVID infection.
Objectives: The aim of this international study was to evaluate the clinical outcomes and identify factors influencing mortality in patients who developed candidemia during their COVID infection.
Background: To have country-wide information about multidrug resistance (MDR) in isolates from community-acquired urinary tract infections (CAUTI) of Turkey, in terms of resistance rates and useful options.
Methods: We used a geocode standard, nomenclature of territorial units for statistics (NUTS), and a total of 1588 community-acquired isolates of 20 centres from 12 different NUTS regions between March 2019 and March 2020 were analysed.
Results: Of the 1588 culture growths, 1269 (79.
Objectives: Bacteraemia during the course of neutropenia is often fatal. We aimed to identify factors predicting mortality to have an insight into better clinical management.
Methods: The study has a prospective, observational design using pooled data from febrile neutropenia patients with bacteraemia in 41 centres in 16 countries.
Article Synopsis
- The study investigates the clinicopathological characteristics and mortality predictors in patients with peritoneal tuberculosis (TBP) using data from 38 medical centers across 13 countries.
- A total of 208 TBP patients were analyzed, with common comorbid conditions including HIV, diabetes, and chronic renal failure; 34 (16.3%) of these patients died from TBP.
- Key mortality risk factors identified include HIV positivity, cirrhosis, advanced age, and specific symptoms, leading to the development of a pioneering mortality predicting model to identify high-risk patients.
Article Synopsis
- Mpox is a zoonotic disease due to the Mpox virus, which was first noted outside its typical regions in Central and West Africa on May 21, 2022.
- A study involving 647 patients across 16 countries found the majority of cases were young males, mostly homosexual-bisexual, with symptoms like rashes, fever, and lymphadenopathy.
- The findings highlight the need for increased awareness and swift public health responses to manage Mpox’s spread beyond endemic regions.
Fever of unknown origin (FUO) is a serious challenge for physicians. The aim of the present study was to consider epidemiology and dynamics of FUO in countries with different economic development. The data of FUO patients hospitalized/followed between 1st July 2016 and 1st July 2021 were collected retrospectively and submitted from referral centers in 21 countries through ID-IRI clinical research platform.
View Article and Find Full Text PDFIntroduction: Although vaccines are the safest and most effective means to prevent and control infectious diseases, the increasing rate of vaccine hesitancy and refusal (VHR) has become a worldwide concern. We aimed to find opinions of parents on vaccinating their children and contribute to available literature in order to support the fight against vaccine refusal by investigating the reasons for VHR on a global scale.
Methodology: In this international cross-sectional multicenter study conducted by the Infectious Diseases International Research Initiative (ID-IRI), a questionnaire consisting of 20 questions was used to determine parents' attitudes towards vaccination of their children.
Background: Broad-spectrum empirical antimicrobials are frequently prescribed for patients with coronavirus disease 2019 (COVID-19) despite the lack of evidence for bacterial coinfection.
Aims: We aimed to cross-sectionally determine the frequency of antibiotics use, type of antibiotics prescribed, and the factors influencing antibiotics use in hospitalized patients with COVID-19 confirmed by polymerase chain reaction.
Study Design: The study was a national, multicenter, retrospective, and single-day point prevalence study.
Article Synopsis
- A machine learning decision support system was developed to improve COVID-19 diagnostics by utilizing routine lab parameters, aiming to reduce misdiagnoses and testing costs.
- The study involved reviewing patient files, focusing on demographic, CT, and lab data from both asymptomatic individuals with negative and positive RT-PCR tests.
- The proposed system demonstrated high accuracy rates in detecting COVID-19, achieving 97.56% through CT image classification using a specific hybrid method (AlexNet-SVM) and 97.86% when incorporating laboratory data.
Background: While global attention has focused largely on the effects of the coronavirus on physical health, the effects of the coronavirus on mental health cannot be ignored. Therefore, this study aims to investigate the effects of COVID-19 disease on mental health and its relationship with other clinical variables.
Methods: In this study, adult patients over 18 years of age who were diagnosed with COVID 19 by real time-polymerized chain reaction (RT-PCR) method in our city were included.
Objectives: The aim of study was to determine the presence of some of the herpesviruses including herpes simplex virus (HSV), Epstein-Barr virus (EBV), and cytomegalovirus (CMV) in adenoid tissues of children with adenoid hypertrophy (AH) and chronic adenoiditis (CA) and to investigate the potential role of the herpesviruses in patogenesis of AH and CA.
Patients And Methods: A total of 72 patients (41 boys, 31 girls; mean age 4 years and 2 months; range 2 to 9 years) who underwent adenoidectomy or adenotonsillectomy (with or without placement of a ventilation tube) in our clinic between October 2007 and May 2008, were included. The patients were divided into two groups, as AH group (n=42) and the CA group (n=30).
Objectives: The aim of this study was to assess the effects of pegylated interferon monotherapy and pegylated interferon+lamivudine combination therapy on auditory functions in patients with chronic hepatitis B (CHB) infection.
Methods: A total of 54 patients with a diagnosis of CHB were grouped into four treatment groups: patients in Group 1 received pegylated interferon-alpha 2a; patients in Group 2 received pegylated interferon-alpha 2a+lamivudine; patients in Group 3 received pegylated interferon-alpha 2b, and patients in Group 4 received pegylated interferon-alpha 2b+lamivudine treatment. The auditory system (using standard and high frequency audiometry) and the vestibulocochlear adverse effects including otalgia, tinnitus, vertigo and imbalance were assessed immediately before the onset of the study, and at the 12th, 24th, and 48th weeks of the study.
[Retropharyngeal abscesses: a retrospective analysis of 10 patients].
Kulak Burun Bogaz Ihtis Derg
August 2010
Objectives: Retropharyngeal abscess is a serious and life-threatening disease due to its anatomic location and potential to obstruct the upper airway. We evaluated the clinical characteristics, diagnosis, and treatment of patients with retropharyngeal abscesses.
Patients And Methods: The study included 10 patients (6 males, 4 females; mean age 9+/-11 years; range 4 months to 32 years) who received medical and surgical treatment with the diagnosis of retropharyngeal abscess.