Publications by authors named "Gulce Itir Percin"
Article Synopsis
- - The third edition of the Flow Cytometry Guidelines offers essential information for conducting flow cytometry experiments, covering immune cell phenotypes and functional assays in both humans and mice.
- - It includes tables that highlight the differences between human and murine cell phenotypes, along with examples of flow cytometry applications related to autoimmune diseases, cancers, and infectious diseases.
- - The guidelines also provide practical tips and common pitfalls to avoid, and are authored by renowned experts in the field, making it a crucial resource for researchers in both basic and clinical settings.
Regulatory mechanisms controlling the pool size of spleen dendritic cells (DC) remain incompletely understood. DCs are continuously replenished from hematopoietic stem cells, and FLT3-mediated signals cell-intrinsically regulate homeostatic expansion of spleen DCs. Here we show that combining FLT3 and CSF1R-deficiencies results in specific and complete abrogation of spleen DCs in vivo.
View Article and Find Full Text PDFRecent advances in single-cell transcriptomics techniques have opened the door to the study of gene regulatory networks (GRNs) at the single-cell level. Here, we studied the GRNs controlling the emergence of hematopoietic stem and progenitor cells from mouse embryonic endothelium using a combination of single-cell transcriptome assays. We found that a heptad of transcription factors (Runx1, Gata2, Tal1, Fli1, Lyl1, Erg and Lmo2) is specifically co-expressed in an intermediate population expressing both endothelial and hematopoietic markers.
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