Report of data on children with non-typhi Salmonella gastroenteritis in a three-year period.

The purpose of this study was to evaluate the clinical and laboratory data of children with acute gastroenteritis caused by non-typhoid Salmonella spp. infections. Clinical (demographic data, symptoms and findings) and laboratory data (stool microscopy, rapid antigen tests, culture, multiplex polymerase chain reaction and blood test results) of children with acute gastroenteritis caused by non-typhoid Salmonella spp.

Hypertransaminasaemia in children with viral gastroenteritis.

We investigated the rates of increase in serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels of patients with rotavirus, norovirus and enteric adenovirus gastroenteritis. Two hundred children with viral gastroenteritis were evaluated for hypertransaminasaemia retrospectively. The patients were between 0 - 17 years (mean ± SD: 5.

Promoter methylation in epithelial-enriched and epithelial-depleted cell populations isolated from breast milk.

Background: Breast cancer is the most frequently diagnosed cancer among Turkish women and both the incidence and associated mortality appear to be increasing. Of particular concern is the percentage of young women diagnosed with breast cancer; roughly 20% of all breast cancer diagnoses in Turkey are in women younger than 40 years. Increased DNA methylation in the promoter region of tumor suppressor genes is a promising molecular biomarker, and human milk provides exfoliated breast epithelial cells appropriate for DNA methylation analyses.

A retrospective analysis of acute gastroenteritis agents in children admitted to a university hospital pediatric emergency unit.

Background: Acute gastroenteritis is responsible observed in all age groups, especially infants and children. The etiology and clinical course of acute gastroenteritis may vary with age and etiological agents. In developing countries, the morbidity and mortality associated with infectious diarrhea is higher in children younger than five-years-of-age.

Annual report on norovirus in children with acute gastroenteritis in 2009 and their genotypes in Turkey.

In order to determine the incidence, seasonal distribution and clinical characteristics of norovirus in children and analyse the genogroups of norovirus, immunochromatography was used to detect the virus in stool samples. Randomly selected subsets of samples were analysed for genogroups with a multiplex polymerase chain reaction method. Seasonal distribution of norovirus, symptoms, physical and laboratory findings of patients and treatment models were evaluated retrospectively in 2009.

Validity of rapid antigen detection testing in group A beta-hemolytic streptococcal tonsillopharyngitis.

Objective: To evaluate the utility of rapid antigen detection testing (RADT) for the diagnosis of group A beta-hemolytic streptococcal tonsillopharyngitis in children, and to detect the sensitivity and specificity of rapid antigen detection of group A beta-hemolytic streptococci from throat specimen compared with throat culture.

Methods: Rapid antigen detection and throat culture results for group A beta-hemolytic streptococci from outpatients attending university hospital between 1st January 2011 and 31st of December 2011 were evaluated retrospectively. The antigen test negative-throat culture positive patients were investigated for streptococcal carriage.

[Evaluation of clinical and laboratory findings of pediatric patients with adenovirus-associated respiratory tract infections].

Upper respiratory tract infections caused by adenoviruses present long lasting fever for five days and elevated acute phase reactant levels. They are generally misdiagnosed as bacterial infections and are mistreated with antibiotics. The diagnosis of adenovirus infections mainly depends on direct antigen tests, virus isolation and detection of viral DNA using polymerase chain reaction (PCR).

Virological and clinical characterizations of respiratory infections in hospitalized children.

Background: The purpose of this study was to determine the incidence and seasonal distribution of viral etiological agents and to compare their clinical manifestations and disease severity, including single and co infections.

Methods: Multiplex reverse-transcription PCR was performed for the detection of viruses in nasopharyngeal aspirat. Disease severity was grouped using a categorization index as very mild/mild, and moderate/severe.

Hospitalizations for pediatric intoxication: a study from Istanbul.

The objective of this study was to describe the epidemiological features of pediatric patients hospitalized for intoxication. Data were collected from the medical records of children < or =14 years of age, admitted for intoxication in 2005-2007. Of the 2989 admissions, 330 (11%) were intoxication cases; 238 (72.