Antitumor efficacy of synthesized Ag-Au nanocomposite loaded with PEG and ascorbic acid in human lung cancer stem cells.

Lung cancer is the leading cause of mortality worldwide of which non-small cell lung carcinoma constitutes majority of the cases. High mortality is attributed to early metastasis, late diagnosis, ineffective treatment and tumor relapse. Chemotherapy and radiotherapy form the mainstay of its treatment.

Retraction of "One-Pot Surface Modification of β-CuO NPs for Biocatalytic Performance against A-549 Lung Carcinoma Cell Lines through Docking Analysis".

[This retracts the article DOI: 10.1021/acsomega.1c02942.

Retraction of "Effect of Reaction Temperature on Shape Evolution of Palladium Nanoparticles and Their Cytotoxicity against A-549 Lung Cancer Cells".

[This retracts the article DOI: 10.1021/acsomega.9b02776.

One-Pot Surface Modification of β-CuO NPs for Biocatalytic Performance against A-549 Lung Carcinoma Cell Lines through Docking Analysis.

The physicochemical approaches and biological principles in bio-nanotechnology favor specially functionalized nanosized particles. Cuprous oxide nanoparticles (β-CuO NPs) of cuprite phase with a little tenorite (CuO) may be very effective in the development of novel therapeutic approaches against several fatalities including A-549 lung carcinoma cell lines. Consequently, the synthesis of β-CuO NPs for the improvement in the therapeutic index and drug delivery application is becoming an effective strategy in conventional anticarcinoma treatment.

Effect of Reaction Temperature on Shape Evolution of Palladium Nanoparticles and Their Cytotoxicity against A-549 Lung Cancer Cells.

Palladium nanoparticles (Pd NPs) of different shapes and sizes have been synthesized by reducing potassium tetrachloropalladinate(II) by l-ascorbic acid (AA) in an aqueous solution phase in the presence of an amphiphilic nonionic surfactant poly ethylene glycol (PEG) via a sonochemical method. Materials have been characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray soectrscopy (EDX), Fourier transform infrared (FTIR), surface-enhanced Raman spectroscopy (SERS), particle distribution, and zeta potential studies. Truncated octahedron/fivefold twinned pentagonal rods are formed at room temperature (RT) (25 °C) while hexagonal/trigonal plates are formed at 65 °C.

Microdiplanol and microdiplane: a new m-anisaldehyde and a new 24-methylcholestanol derivative from the endophytic fungus Microdiplodia sp.

Phytochemical investigation of the endophytic fungus Microdiplodia sp. afforded a new m-anisaldehyde derivative named microdiplanol (1) and a new 24-methylcholestanol derivative named microdiplane (2). Their structures were confirmed by a comprehensive analysis of 1D and 2D NMR and mass spectrometric data.

Prevalence and covariates of electrocardiographic left ventricular hypertrophy in diabetic patients in Tanzania.

Background: Left ventricular hypertrophy (LVH) has been demonstrated to be a powerful predictor of cardiovascular (CV) morbidity and mortality in diabetic as well as hypertensive patients. However, less is known about the prevalence of electrocardiographic LVH (ECG-LVH) and its relation to other CV risk factors in diabetic patients in sub-Saharan Africa. Therefore, the aim was to assess the prevalence of ECG-LVH in diabetic patients in Dares Salaam, Tanzania, and its relation to other cardiovascular risk factors.

Clinical outcome of diabetes patients hospitalized with foot ulcers, Dar es Salaam, Tanzania.

Aims: To determine the prevalence rate, clinical features, risk factors, and clinical outcome of foot ulcers in diabetes patients admitted to Muhimbili National Hospital, Dar es Salaam, Tanzania.

Methods: A prospective cohort study of newly hospitalized, adult diabetes patients with foot ulcers was conducted during January 1997 to December 1998 (study period). Detailed clinical and epidemiological data were recorded for each patient, followed by a comprehensive physical examination.