[Antibiotic properties of Lactobacillus acidophilus, "Narine" strain, and the ways for their improvement].

L. acidophilus strain 317/402 "Nariné" shows high antimicrobial activity with respect to pathogenic microorganisms. The degree of the activity of lactobacilli depends on cultivation conditions and the composition of the culture medium and its acidity, age of the culture, conditions of technological process, etc.

[Optimization of culture media and conditions for cultivating Erwinia sp., a producer of fumarase and aspartase].

Mathematical methods of experimental design were used to determine the optimal concentrations of nutrient medium components, aeration conditions, and pH providing for the maximum biomass yields, as well as fumarase and aspartase activities, during submerged cultivation of Erwinia sp. The data showed that different concentrations of carbon source (molasses) and pH of the nutrient medium were required to reach the maximum yields of fumarase and aspartase. Calculations suggested that the combination of these optimized factors would result in 3.

[Pathogenesis of salmonelloses. Fate of the agent in the early stages of the experimental infectious process].

The fate of S. typhimurium was followed during the first 5 hours after infection, and a high invasive activity of Salmonella was revealed. After the oral and enteral infection of the animals with several billion organisms, the latter penetrated the blood and internal organs within 10 minutes.