Yi-Shen-Hua-Shi granule ameliorates diabetic kidney disease by the "gut-kidney axis".

Ethnopharmacological Relevance: Yi-Shen-Hua-Shi (YSHS) granule is an effective prescription widely used in traditional Chinese medicine to treat diabetic kidney disease (DKD), its exact efficacy in treating DKD has been confirmed but the underlying regulatory mechanism has not been fully elucidated.

Aim Of The Study: To explore the mechanism by which YSHS granule regulates intestinal flora and serum metabolites and then regulates renal mRNA expression through the "gut-kidney axis", so as to improve DKD.

Materials And Methods: 40 rats were divided into five groups: Normal group (N) (normal saline), model group (M) (STZ + normal saline), YSHS granule low-dose group (YL) (STZ + 2.

The Application Effect of Evidence-Based Care in Gastrointestinal Surgical Pipeline Nursing.

With the improvement of the higher nursing education system, the overall quality and work ability of clinical nurses have also been significantly improved. Most nursing staff have a positive attitude towards evidence-based nursing medicine but lacking of the knowledge and skills about evidence-based nursing. Clinical nurses are still short of the ability to evaluate relevant research data, which is one of the cause of interference for the clinical nurses to use the latest research results reasonably and effectively at present.