Deciphering the inhibitory mechanisms of didecyldimethylammonium chloride on microalgal removal of fluoxetine: Insights from the alterations in cell surface properties and the physio-biochemical and molecular toxicity.

The COVID-19 pandemic has increased the co-occurrence of quaternary ammonium compounds (QACs) and antidepressants in aquatic environments. Microalgae are sustainable and cost-effective candidates for removing emerging pollutants. QACs have a robust ability to adsorb on cell surface and alter membrane permeability, but little is known about the influence of QACs on microalgal bioremediation of co-existing pollutants like antidepressants.

Long COVID patients' brain activation is suppressed during walking and severer symptoms lead to stronger suppression.

This research aims to study the factors contributing to Long COVID and its effects on motor and cognitive brain regions using population surveys and brain imaging. The goal is to provide new insights into the neurological effects of the illness and establish a basis for addressing neuropsychiatric symptoms associated with Long COVID. Study 1 used a cross-sectional design to collect data on demographic characteristics and factors related to Long COVID symptoms in 551 participants.

Identifying biomarkers related to motor function in chronic stroke: A fNIRS and TMS study.

Background: Upper limb motor impairment commonly occurs after stroke, impairing quality of life. Brain network reorganization likely differs between subgroups with differing impairment severity. This study explored differences in functional connectivity (FC) and corticospinal tract (CST) integrity between patients with mild/moderate versus severe hemiplegia poststroke to clarify the neural correlates underlying motor deficits.

Electroencephalography oscillations can predict the cortical response following theta burst stimulation.

Background: Continuous theta burst stimulation and intermittent theta burst stimulation are clinically popular models of repetitive transcranial magnetic stimulation. However, they are limited by high variability between individuals in cortical excitability changes following stimulation. Although electroencephalography oscillations have been reported to modulate the cortical response to transcranial magnetic stimulation, their association remains unclear.

Causal Association of Cytokines and Growth Factors with Stroke and Its Subtypes: a Mendelian Randomization Study.

Cytokines and growth factors contribute to nerve growth and angiogenesis and are associated with the development of vascular disease. This Mendelian randomization (MR) study was designed to examine the causal relationship between factors associated with stem cell paracrine mechanisms and with stroke and its subtypes. We used pooled statistics on cytokine levels from three studies (INTERIAL, Olink Proseek CVD array, and KORA) encompassing 7795 participants in Europe.

Neurophysiological characterization of stroke recovery: A longitudinal TMS and EEG study.

Aims: Understanding the neural mechanisms underlying stroke recovery is critical to determine effective interventions for stroke rehabilitation. This study aims to systematically explore how recovery mechanisms post-stroke differ between individuals with different levels of functional integrity of the ipsilesional corticomotor pathway and motor function.

Methods: Eighty-one stroke survivors and 15 age-matched healthy adults participated in this study.

Non-invasive brain stimulation effectively improves post-stroke sensory impairment: a systematic review and meta-analysis.

More than half of stroke patients experience sensory dysfunction that affects their quality of life. Previous training modalities are ineffective in improving sensory function. In contrast, non-invasive brain stimulation (NIBS) is a new promising intervention for stroke rehabilitation.

An ultralight and flexible nanofibrillated cellulose/chitosan aerogel for efficient chromium removal: Adsorption-reduction process and mechanism.

Heavy metals in water are critical global environmental problems. In particular, the anionic heavy metal chromium (Cr) has carcinogenic and genotoxic risks on human health. To this end, an ultralight and flexible nanofibrillated cellulose (NFC)/chitosan (CS) aerogel was developed only by freeze-drying combined with physical thermal cross-linking for efficient one step co-removal of Cr(VI) and Cr(III).

Functionally-designed floatable amino-modified ZnLa layered double hydroxides/cellulose acetate beads for tetracycline removal: Performance and mechanism.

The over-reliance on tetracycline antibiotics (TC) in the animal husbandry and medical field has seriously affected the safety of the ecological environment. Therefore, how to effectively treat tetracycline wastewater has always been a long-term global challenge. Here, we developed a novel polyethyleneimine (PEI)/Zn-La layered double hydroxides (LDH)/cellulose acetate (CA) beads with cellular interconnected channels to strengthen the TC removal.

Individual differences in beta-band oscillations predict motor-inhibitory control.

Objective: The ability of motor-inhibitory control is critical in daily life. The physiological mechanisms underlying motor inhibitory control deficits remain to be elucidated. Beta band oscillations have been suggested to be related to motor performance, but whether they relate to motor-inhibitory control remains unclear.

Effects of repetitive transcranial magnetic stimulation on sequelae in patients with chronic stroke: A systematic review and meta-analysis of randomized controlled trials.

Background: Stroke is the second leading cause of death worldwide, with a large proportion of survivors suffering from motor dysfunction and neuropsychiatric sequelae. Repetitive transcranial magnetic stimulation (rTMS) is a promising stroke rehabilitation intervention and is effective in improving neurological system function in stroke patients. In the current systemic review and meta-analysis, an overview of the most recent studies regarding the effectiveness of rTMS's potential to help chronic stroke patients recover from sequelae was provided.

Anthropogenic pollution discharges, hotspot pollutants and targeted strategies for urban and rural areas in the context of population migration: Numerical modeling of the Minjiang River basin.

Unprecedented urbanization-induced population migration in China severely affects the scale and geographic distribution of anthropogenic pollutant discharge. Understanding how pollutant discharge patterns respond to population migration can help guide future efforts to maintain water sustainability. Here, based on a new calculation framework with 18 dynamic parameters designed for anthropogenic discharges, we finely tracked and visualized the effects of population migration on the spatial and temporal changes in anthropogenic discharge from 1980 to 2019 in the Minjiang River basin.

Continuous Theta-Burst Stimulation Promotes Paravascular CSF-Interstitial Fluid Exchange through Regulation of Aquaporin-4 Polarization in APP/PS1 Mice.

Amyloid- (A) deposition plays a crucial role in the occurrence and development of Alzheimer's disease (AD), and impaired A clearance is the leading cause of A deposition. Recently, studies have found that the glymphatic system performs similar functions to the peripheral lymphatic system. Glymphatic fluid transport mainly consists of cerebrospinal fluid (CSF) entering the brain from the paravascular space (PVS) by penetrating arteries and CSF and interstitial fluid exchanging mediated by aquaporin-4 (AQP4).

Effects of repetitive transcranial magnetic stimulation on upper-limb and finger function in stroke patients: A systematic review and meta-analysis of randomized controlled trials.

Background: Repetitive transcranial magnetic stimulation (rTMS) is a promising intervention for stroke rehabilitation. Several studies have demonstrated the effectiveness of rTMS in restoring motor function. This meta-analysis aimed to summarize the current evidence of the effect of rTMS in improving upper limb function and fine motor recovery in stroke patients.

Rapid purification of As(III) in water using iron-manganese composite oxide coupled with sulfite: Importance of the SO radicals.

Manganese (Mn)-containing composite metal adsorbents are very effective at removing arsenite (As(III)) from contaminated water, however, the low removal speed and oxidation efficiency have limited their further application. In this study, a nonhomogeneous catalytic oxidation-adsorption system was constructed by coupling iron-manganese composite oxide (FeMnO) with sulfite (S(IV)) to enhance the recovery of oxidative capacity and accelerate the removal of As(III). Experimental results showed that the FeMnO/S(IV) system decreased the As(III) concentration from 1079 to <10 µg/L within 10 min and almost completely oxidized As(III) to As(V).

Intermittent Theta Burst Stimulation Increases Natural Oscillatory Frequency in Ipsilesional Motor Cortex Post-Stroke: A Transcranial Magnetic Stimulation and Electroencephalography Study.

Objective: Intermittent theta burst stimulation (iTBS) has been widely used as a neural modulation approach in stroke rehabilitation. Concurrent use of transcranial magnetic stimulation and electroencephalography (TMS-EEG) offers a chance to directly measure cortical reactivity and oscillatory dynamics and allows for investigating neural effects induced by iTBS in all stroke survivors including individuals without recordable MEPs. Here, we used TMS-EEG to investigate aftereffects of iTBS following stroke.

The Effects of Intermittent Theta Burst Stimulation on Functional Brain Network Following Stroke: An Electroencephalography Study.

Intermittent theta burst stimulation (iTBS) is a special form of repetitive transcranial magnetic stimulation (rTMS), which effectively increases cortical excitability and has been widely used as a neural modulation approach in stroke rehabilitation. As effects of iTBS are typically investigated by motor evoked potentials, how iTBS influences functional brain network following stroke remains unclear. Resting-state electroencephalography (EEG) has been suggested to be a sensitive measure for evaluating effects of rTMS on brain functional activity and network.

Brain Network to Placebo and Nocebo Responses in Acute Experimental Lower Back Pain: A Multivariate Granger Causality Analysis of fMRI Data.

: Placebo and nocebo responses are widely observed. Herein, we investigated the nocebo hyperalgesia and placebo analgesia responses in brain network in acute lower back pain (ALBP) model using multivariate Granger causality analysis (GCA). This approach analyses functional magnetic resonance imaging (fMRI) data for lagged-temporal correlation between different brain areas.

Sex Differences in the Blood Oxygen Level-Dependent Signal to Placebo Analgesia and Nocebo Hyperalgesia in Experimental Pain: A Functional MRI Study.

Objective: Placebo as well as nocebo responses are widely found in scientific research and clinical practice. Growing evidence suggests sex differences in placebo as well as nocebo responses. However, data concerning this question are still insufficient.

The Corticospinal Excitability Can Be Predicted by Spontaneous Electroencephalography Oscillations.

Transcranial magnetic stimulation (TMS) has a wide range of clinical applications, and there is growing interest in neural oscillations and corticospinal excitability determined by TMS. Previous studies have shown that corticospinal excitability is influenced by fluctuations of brain oscillations in the sensorimotor region, but it is unclear whether brain network activity modulates corticospinal excitability. Here, we addressed this question by recording electroencephalography (EEG) and TMS measurements in 32 healthy individuals.

Self-enhanced and efficient removal of As(III) from water using Fe-Cu-Mn composite oxide under visible-light irradiation: Synergistic oxidation and mechanisms.

Here, we prepared a novel nanostructured Fe-Cu-Mn composite oxide (FCMO) adsorbent using an ultrasonic coprecipitation method. The maximum adsorption capacity of As(III) and As(V) reached 158.5 and 115.

Personality differences in brain network mechanisms for placebo analgesia and nocebo hyperalgesia in experimental pain: a functional magnetic resonance imaging study.

Background: Placebo and nocebo responses have been increasingly gaining the attention of clinical and scientific researchers. Inconsistent conclusions from current studies indicate that different factors potentially affect both placebo and nocebo responses. Increasing evidence suggests that personality differences may affect the mechanisms of both two responses.

Short intracortical facilitation associates with motor-inhibitory control.

The ability of motor-inhibitory control is important in daily life. Inhibitory control deficits are commonly observed in psychiatric conditions with enhanced impulsivity. The physiological mechanisms underlying the inhibitory control deficits are not well elucidated.

Personality Differences of Brain Networks in Placebo Analgesia and Nocebo Hyperalgesia: A Psychophysiological Interaction (PPI) Approach in fMRI.

It is generally believed that the placebo response can elicit an analgesic effect, whilst the nocebo response can elicit a hyperalgesia effect in pain. Placebo analgesia and nocebo hyperalgesia effects are increasing concerns for researchers. Growing evidence suggests personality differences have an impact on both placebo and nocebo effects.

Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model.

Background: Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting inflammatory response in NeuP. Recently, the triggering receptor expressed on myeloid cells 2 (TREM2) expressed by microglia was identified as a critical factor of inflammation in nervous system diseases.