Publications by authors named "Guiyu Zhan"
Article Synopsis
- Ischemic stroke (IS) poses a significant risk to health and can be worsened by cerebral ischemia/reperfusion injury (CIRI), which triggers neuroinflammation and oxidative stress; the study investigates whether sweet tea (ST) can protect against CIRI.
- Experiments were conducted on male SD rats with CIRI, assessing brain damage indicators and identifying therapeutic pathways affected by ST using various analytical methods.
- Results showed that ST treatment improved brain health by reducing oxidative stress and inflammation, specifically targeting the PI3K/AKT/NF-κB pathway and NLRP3-mediated pyroptosis, indicating its potential protective effects against CIRI.
Trilobatin, a novel natural food additive, exerts a protective effect on acute liver injury. However, whether Trilobatin can protect against alcoholic liver disease (ALD) has not been elucidated. This research is intended to ascertain the impact of Trilobatin on ALD in mice and decipher the potential underlying mechanisms.
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