Feeling low: How social media influences employees' knowledge hidings and innovative behavior.

Prior research has identified both positive and negative consequences arising from the widespread integration of social media within the organizations. The present research suggests that upward social comparison (USC) in social media is related to psychological disengagement resulting in knowledge hiding and lower innovative behavior of individuals. It further suggests that mindfulness mitigates the impact of USC in social media.

KISS-1 knockdown inhibits cell growth, migration, and invasion in HTR-8/SVneo cells by regulating the GRP54-mediated PI3K/AKT signaling pathway.

Recurrent spontaneous abortions (RSA) affect reproductive health and increase the risk of subsequent abortions. To investigate the role of KISS-1/GPR-54 signaling in RSA progression. Villus tissue was collected from RSA patients, and human trophoblastic HTR-8/SVneo cells were used.

[Analysis of genetic diversity and biological functional site of HIV-1 gp120 from a patient with AIDS dementia complex].

To explore the relationship between the genetic diversity and biological functional site of human immunodeficiency virus HIV-1 gp120 and the pathogenesis of AIDS dementia complex (ADC), the full length sequences of gp120 gene was amplified with PCR from genomic DNA which was extracted from lymphoid and different brain department (periaortic lymphoid, temporal gray/white matter junction, periventricular tissue, choroids plexus, occipital white matter and occipital gray/white matter junction.) of a patient who died of ADC. PCR products were cloned into the pGEM-T vector and positive clones were sequenced.

Amino acid substitutions in leucine zipper motif in the F-specific domain of human parainfluenza virus 3 HN protein play important roles in the protein function.

Objectives: To explore the effects of leucine zipper motif in F-specificity domain of human parainfluenza virus 3 (hPIV3) HN protein on the membrane fusion promotion activity.

Methods: Site-directed mutagenesis was performed to generate mutants in leucine zipper motif of hPIV3 HN protein. Combined mutants were obtained from individual mutants.

[Cloning and sequence analysis of envelope glycoprotein G2 gene of hantavirus in Shandong province].

Objective: To construct the cloning vector of glycoprotein G2 gene of hantavirus (HV), to analyze the sequence of G2 gene by the phylogenetic tree, and to study the differences among glycoprotein G2 genes from the world around.

Methods: Envelope glycoprotein G2 gene was amplified from four specimens of Shandong province by RT-PCR, and the product recombined into the PMD-18T vector. The clones that carry the G2 gene were identified.

Genetic properties of medium (M) and small (S) genomic RNA segments of Seoul hantavirus isolated from Rattus norvegicus and antigenicity analysis of recombinant nucleocapsid protein.

A novel isolate of Seoul (SEO) hantaviruses was detected and identified in Rattus norvegicus in Shandong Province, China and designated as JUN5-14. The partial M segment and the coding region of nucleocapsid protein (NP) in the S segment of JUN5-14 were PCR-amplified and sequenced. Nucleotide sequence analysis of the partial M segment (300 bp) revealed that JUN5-14 isolate was closely related to former SEO isolates in Shandong (97.

Effects of heptad repeat regions of f protein on the specific membrane fusion in paramyxoviruses.

Objectives: To identify the effects of heptad repeat regions (HR1 and HR2) of F on the specific membrane fusion in paramyxoviruses.

Methods: Site-directed mutagenesis was used to create same enzyme sites on the F genes of Newcastle disease virus (NDV) and human parainfluenza virus (hPIV). Gene recombination was used to get chimeric F proteins NDV C-HR1 and hPIV C-HR1 by exchanging HR1 fragments each other; NDV C-HR2 and hPIV C-HR2 were also obtained by the same way.

[Studies on anti-HSV effect of Ficus carica leaves].

Objective: To study the anti-HSV effect of the extract from the leaves of Ficos carica.

Methods: The effective ingredient was extracted from the leaves of Ficus carica, and the anti-virus effect was observed on Hep-2, BHK21 and PRK cells.

Results: The water extract from the leaves of Ficus carica possessed distinct anti-HSV-1 effect.

[Inhibition effects of rhubarb ethanol extract on herpes simplex virus infection in vivo].

Objective: To know the anti-viral effects of rhubarb ethanol extract (REE) on herpes simplex virus(HSV) infection in vivo.

Methods: BALB/c mice inoculated from tail vein with 0.15 ml of HSV (TCID50=10(3)) were injected hypodermically with REE next day.

Characteristics and mechanisms of isolated rubella virus, strain JR23: infection of the central nervous system of BALB/c mice.

Objective: To investigate the correlation between rubella virus (RuV) antigen in peripheral lymphocytes, the immune status and RuV infection in the central nervous system (CNS).

Methods: BALB/c mice were used as a model and treated with immunoaffecting medicines. Then, the mice were infected with RuV via the abdominal cavity, and the antigen level in peripheral lymphocytes was examined 1, 3, 7 and 14 days postinfection.

[Immune status of BALB/c mice and rubella virus JR23 strain infection of central nervous system].

Background: To investigate the relationship between immune status and rubella virus (RV) infection of central nervous system (CNS).

Methods: BALB/c mice were given dexamethaxone and cytoxan before RV JR23 strain infection. Immune functions and RV invasion to CNS were assayed at 21 days postinfection via abdominal cavity and their relationship was analyzed.