Sonographic features of uterine fibroids that predict the ablation rate and efficacy of high-intensity focused ultrasound.

Objective: This study aimed to identify the sonographic indicators that predict the ablation rate and efficiency of uterine fibroids during high-intensity focused ultrasound (HIFU) treatment.

Methods: In this retrospective study, we analyzed the clinical data of patients with uterine fibroids who underwent HIFU treatment at Fujian Provincial Hospital between April 2019 and April 2022. Routine abdominal ultrasound examinations were performed to observe potential indicators before the HIFU treatment.

Silencing MFN2 Drives WNT/β-catenin Nucleation to Reduce Sorafenib Sensitivity in Hepatocellular Carcinoma Cells.

Objective: Mitofusin-2 (MFN2) is a mitochondrial membrane protein that plays a critical role in regulating mitochondrial fusion and cellular metabolism. To further elucidate the impact of MFN2, this study aimed to investigate its significance on hepatocellular carcinoma (HCC) cell function and its potential role in mediating chemosensitivity.

Methods: This study investigated the effects of silencing and overexpressing MFN2 on the survival, proliferation, invasion and migration abilities, and sorafenib resistance of MHCC97-L HCC cells.

[Evaluation of implementation effect of schistosomiasis control program in Jiangsu Province from 2010 to 2015].

Objective: To evaluate the actual effect of the schistosomiasis control program in Jiangsu Province from 2010 to 2015.

Methods: A total of 67 schistosomiasis-endemic counties in 10 cities were selected, and a combination of retrospective investigation and on-site investigation was adopted to collect and record the epidemic data of the counties from 2010 to 2015, and a retrospective survey database of epidemic situation was established. The effects of integrated control strategies with both snail control and infection source control were evaluated.

[Epidemic situation and diagnosis and treatment of severe falciparum malaria in Nantong City].

Objective: To retrospectively analyze the epidemic situation and diagnosis and treatment of severe falciparum malaria in Nantong City, summarize the causes of severe falciparum malaria, and evaluate the effect of diagnosis and treatment, so as to provide the evidence for formulating the practical treatment measures for this disease.

Methods: All the data of falciparum malaria cases in Nantong City from 2009 to 2016 were collected and analyzed for the onset time, diagnosis process and treatment of the disease.

Results: A total of 359 malaria cases, including 289 falciparum malaria cases, were reported in Nantong City from 2009 to 2016, including 26 severe falciparum malaria cases.

The challenge of maintaining microscopist capacity at basic levels for malaria elimination in Jiangsu Province, China.

Background: Local malaria transmission has decreased rapidly since the National Malaria Elimination Action Plan was launched in China in 2010. However, imported malaria cases from Africa and Southeast Asia still occur in China due to overseas laborers. Diagnosis by microscopy is the gold standard for malaria and is used in most hospitals in China.

[Study on snails infected with miracidia under different conditions in snail-existent non-endemic areas of schistosomiasis in Nantong City].

Objective: To understand the forming cause of the snail-existent non-endemic areas of schistosomiasis (SENEAS), and to verify the conclusion of previous studies, so as to provide the evidence for schistosomiasis monitoring in such areas in Nantong City, Jiangsu Province.

Methods: The controlled field tests were carried out to observe the snails artificially infected by schistosome miracidia in SENEAS. The influence of the soil from SENEAS and the endemic areas on snails artificially infected by miracidia were observed.

[Investigation on current situation of malaria blood examinations in township-level hospitals of Nantong City].

Objective: To understand the quality of malaria blood examinations in township-level hospitals, so as to provide the evidence for continuing the malaria blood examinations in the stage of post-malaria elimination.

Methods: A total of 64 township hospitals were investigated and 640 negative malaria blood slides were scored individually according to 10 indicators in "Malaria Elimination Technical Scheme" in 2013 and 2014. The single and multiple indicators were calculated, and the work of blood examinations and situation of technicians were investigated.

Ultrasound measurement of optic nerve diameter and optic nerve sheath diameter in healthy Chinese adults.

Background: Measurement of optic nerve sheath diameter (ONSD) is a fast and non-invasive method in detecting elevated intracranial pressure. However, the reported normal range of ONSD was inconsistent. The objective of the study was to determine the normal range of ONSD in healthy Chinese adults.

Effects of glutamine on oxidative stress and nuclear factor-κB expression in the livers of rats with nonalcoholic fatty liver disease.

The aim of this study was to investigate the effects of glutamine on the histomorphology of the liver, oxidative stress and nuclear factor-κB (NF-κB) expression in the development of nonalcoholic fatty liver disease (NAFLD). NAFLD was induced in rats by a high-fat diet, and rats in the treatment group were subjected to oral administration of glutamine (1 g/kg/day). Rats from the treatment, model and normal control groups were assessed after 8 and 12 weeks (n=6 per group at each time-point).

[Survey of Toxoplasma gondii infection among pregnant women in Jiangsu Province, China].

Objective: To understand the situation of Toxoplasma gondii infection among pregnant women in Jiangsu Province.

Methods: The pregnant women from 7 cities in Jiangsu Province were involved in this survey and the information was recorded according to the request of unified admission information of the case questionnaire of toxoplasmosis in Jiangsu Province. The specific antibodies IgM and IgG to Toxoplasma gondii in sera of these pregnant women were tested by ELISA.

[Surveillance on schistosomiasis of boat fishermen along Yangtze River in Nantong City from 2006 to 2010].

Objective: To discover the imported infection sources of schistosomiasis as early as possible.

Methods: Boat fishermen were screened with DDIA and the positive ones were tested by the hatching method or Kato-Katz technique.

Results: From 2006 to 2010, 2 951 boat fishermen along the Yangtze River in Nantong City were tested with DDIA for schistosomiasis and 17 positive cases were found, while 1 case was positive in the feces examination.

[Effect of intermittent irrigation in paddy fields on mosquito control].

Objective: To investigate the effects of intermittent irrigation in paddy fields on mosquito control and the impact on growth and yield of rice.

Methods: The paddy fields were divided into an experimental group and a control group. In the same context of other measures, the experimental group was performed with intermittent irrigation and the control group with conventional irrigation.

[Analysis of imported falciparum malaria cases of Nantong City from 2001 to 2010].

Objective: To analyze the characteristics of imported falciparum malaria cases of Nantong City in the recent ten years so as to provide the evidence for improving prevention and control of malaria in the future.

Methods: The data about imported falciparum malaria cases of Nantong City from 2001 to 2010 were collected and analyzed for the characteristics and distribution of the patients by the retrospective method. RESULTS; There were 79 imported falciparum malaria cases in the last 10 years.