Publications by authors named "Guirou Nouhoum"
Introduction: Oculo-orbital tumors are common. Their clinical and histological features are multiple. The management of oculo-orbital tumors is a real challenge in sub-Saharan Africa, especially in our context.
View Article and Find Full Text PDFAmong ocular infections, trachoma is the main cause of blindness. Repeated conjunctival Chlamydia trachomatis infections lead to trichiasis, corneal opacification, and visual impairment. Surgery is often needed to relieve discomfort and preserve vision; however, a high postoperative trachomatous trichiasis (PTT) rate has been observed in various settings.
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- The study aimed to evaluate how genetic variations (polymorphisms) in CYP2B6 and CYP3A4 affect the health responses of HIV-positive patients, focusing on their viral load and immune system functioning.
- A total of 153 patients were involved, and assessments were made on their viral loads and CD4 T cell counts at the start and after six months, utilizing TaqMan genotyping assays to identify genetic markers.
- Results indicated that certain genetic variations, particularly in CYP2B6, correlate with viral load suppression and increases in CD4 cell counts, suggesting these genetic markers could help predict treatment outcomes in HIV patients.
Background: Ocular damage, including damage to the conjunctiva, lacrimal gland, eyelids, and orbit, caused by Schistosoma haematobium is sporadic. We report a clinical case of orbital migration of schistosome eggs.
Case Presentation: A 14-year-old boy of Malian nationality presented with a painless swelling of the upper right eyelid, which had been gradually increasing for approximately 3 months.
Article Synopsis
- Primary open-angle glaucoma is more common and severe in people of African descent compared to those of European or Asian ancestry, yet they are often overlooked in genetic research on this condition.
- The study conducts a genome-wide association study (GWAS) involving nearly 10,000 participants from various countries to identify genetic links to the disease.
- Results suggest significant genetic variants associated with primary open-angle glaucoma, highlighting the need for more focused research on affected populations for better understanding and treatment options.
Article Synopsis
- * A clinical case is presented of a 6-year-old boy with bilateral papillary coloboma who has no other malformations, occurring in a family with two children.
- * The child's background includes a normal birth and current immunization, while his father's and sister's eye exams were normal, although their mother has strabismus in her right eye.
Papilledema is a fluid and/or axonal swelling of the optic nerve head due to a blockage of axoplasmic flow at the level of the cribriform plate. We report the case of a 17-year old adolescent girl with bilateral papilledema secondary to idiopathic intracranial hypertension.
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