Combined treatment with and activated the Bax/Bcl-2 and Caspase-3 signal pathways in papillary thyroid carcinoma cells.

To explore the effect of (PV) combined with (RB) on apoptosis of papillary thyroid carcinoma cells. Our study was divided into four groups: the control group, the PV group, the RB group, and the PV combined with the RB group. The viability of cells from different treatment groups was assessed by the CCK-8 assay.

Comparison of Rapid Rehabilitation after Anterior Cruciate Ligament Reconstruction with Tensioning Technique and Traditional Rehabilitation.

To investigate the efficacy of a fast rehabilitation program for the recovery of knee joint function after arthroscopic autologous hamstring tendon transplantation for reconstruction of the anterior cruciate ligament (ACL), from January 1, 2017, to March 31, 2019, a total of 65 patients with ACL injury were randomly divided into a study group and a control group. Both groups were treated with autologous hamstring tendon to reconstruct the anterior cruciate ligament, arthroscopic transplantation, and decompression techniques. The research group was treated with a fast rehabilitation program.

Effects of Tissue-engineered Bone by Coculture of Adipose-derived Stem Cells and Vascular Endothelial Cells on Host Immune Status.

Aim: The study aimed to explore the effects of tissue-engineered bone constructed with partially deproteinized biologic bone (PDPBB) and coculture of adipose-derived stem cells (ADSCs) and vascular endothelial cells (VECs) on host immune status, providing a very useful clue for the future development of bone engineering.

Methods: Tissue-engineered bones constructed by PDPBB and ADSCs, VECs or coculture of them were implanted into the muscle bag of bilateral femurs of Sprague-Dawley rats. Partially deproteinized biologic bone alone and blank control were also implanted.

The use of a 3D-printed individualized navigation template to assist in the anatomical reconstruction surgery of the anterior cruciate ligament.

Background: To explore the location accuracy and early clinical outcomes of using a 3D-printed individualized navigation template to assist in the reconstruction of the anterior cruciate ligament (ACL).

Methods: A single center randomized control study was conducted. Patients with ACL injury were treated with a conventional operation or an operation assisted by a 3D-printed individualized navigation template (the 3D group).

Construction of tissue engineering bone with the co‑culture system of ADSCs and VECs on partially deproteinized biologic bone : A preliminary study.

Scaffold‑based bone tissue engineering has therapeutic potential in the regeneration of osseous defects. The present study aimed to explore the adhesion and cell viability of a co‑culture system composed of vascular endothelial cells PI/Annexin V represents early apoptotic cells, and PI/Annexin V represents late apoptotic cells (VECs) and adipose‑derived stem cells (ADSCs) on partially deproteinized biologic bone (PDPBB) , and determine the optimum time period for maximum cell viability that could possibly be used for standardizing the scaffold transplant into the system. VECs and ADSCs were isolated from pregnant Sprague‑Dawley rats and confirmed by immunostaining with von Willebrand factor and CD90, respectively.

Static and dynamic alterations in the amplitude of low-frequency fluctuation in patients with amyotrophic lateral sclerosis.

Background: Static changes in local brain activity in patients suffering from amyotrophic lateral sclerosis (ALS) have been studied. However, the dynamic characteristics of local brain activity are poorly understood. Whether dynamic alterations could differentiate patients with ALS from healthy controls (HCs) remains unclear.

Dynamic alterations of spontaneous neural activity in patients with amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a multi-system disease featured by movement disorder. Studies on ALS using static neuroimaging indexes demonstrated inconsistent results. However, recent work indicated that the intrinsic brain activity was time-varying, and the abnormal temporal dynamics of brain activity in ALS remains unknown.

Effect of SDF-1 with biphasic ceramic-like bone graft on the repair of rabbit radial defect.

Background: This study aimed to investigate the effects of stromal cell-derived factor-1 (SDF-1) on biphasic ceramic-like biologic bone (BCBB) in vivo on the repair of large segment bone defect in rabbits.

Methods: A large-segment radius defect model of the rabbits was constructed. In the experimental group, BCBB with SDF-1 sustained-release system were implanted into the bone defect site.