Mendelian Randomization Analysis Reveals a Causal Relationship Between Membranous Nephropathy and the Gut Microbiome.

Background: With the increasing prevalence of membranous nephropathy (MN), the gut microbiome (GM) is increasingly implicated in its cause, yet the intricate mechanisms remain unclear. Whether changes in the diversity and richness of gut microbial populations among MN patients contribute to disease prevalence is still unanswered, necessitating further exploration into the potential causative link between the GM and MN.

Methods: We conducted a comprehensive bidirectional Mendelian randomization (MR) study.

Hydrogel Extinguishants.

The exploitation of clean and efficient fire extinguishing materials has substantial implications for improving disaster prevention, mitigation, and relief capabilities, maintaining public safety, and protecting people's lives and property as well as the natural environment. Natural polymer hydrogel with high water containment, excellent film formation, high heat insulation, ecofriendliness, and degradability has huge potential in achieving new breakthroughs for developing clean and efficient fire extinguishing materials and products. In recent years, the exploitation of hydrogel extinguishing materials and the fabrication of products has attracted great attention, gradually replacing traditional fire extinguishing products.

Nano-Structure Evolution and Mechanical Properties of AlCoCrFeNi (x = 0, 0.3, 0.7, 1.0, 1.3) High-Entropy Alloy Prepared by Mechanical Alloying and Spark Plasma Sintering.

The AlCoCrFeNi (x = 0, 0.3, 0.7, 1.

Precipitation Behavior of the Topologically Close-Packed Phase in the DD5 Superalloy during Long-Term Aging.

The precipitation behaviors of the topologically close-packed (TCP) phases in the bicrystal DD5 superalloy have been investigated. The results showed that the [001] crystallographic orientations are consistent with that of adjacent grains; however, the direction of the needle-like TCP phases is not consistent with that of the phase channels. The angle between needle-like TCP phases and phase channels is 45°, but the angle between the needle-like TCP phases of the adjacent grains is equal to the misorientation of the adjacent grains.