Publications by authors named "Guiqing Shi"
Article Synopsis
- About 10%-30% of Hodgkin's lymphoma patients experience relapse or treatment resistance after first-line therapy, making subsequent treatment difficult, particularly after failure of Brentuximab vedotin (BV) and immune checkpoint inhibitors (ICIs).
- A study analyzed 19 patients with relapsed/refractory Hodgkin's lymphoma who underwent radiotherapy after BV or ICI failure, finding a 100% overall response rate and a median duration of response of 17.2 months.
- The 1-year progression-free survival and overall survival rates were 84.4% and 100%, respectively, with no serious adverse events reported, demonstrating that radiotherapy is both effective and safe for this patient group.
Article Synopsis
- Radiotherapy (RT) is a local treatment option for patients with refractory or relapsed aggressive B-cell lymphomas, but the effectiveness of hypofractionated RT had not been previously confirmed.
- A study analyzed 30 patients who received hypofractionated RT, showing a high objective response rate (90%) and complete response rate (80%), with promising one-year overall survival (81.8%) and progression-free survival (66.3%).
- The findings indicate that hypofractionated RT is both effective and tolerable, particularly for patients with localized residual disease, as no serious side effects were reported.
Background: Limited evidence supports the omission of routine bone marrow (BM) examination (biopsy and aspiration) in patients with nasal-type extranodal NK/T-cell lymphoma (ENKTCL). This study was aimed at assessing whether BM examination provides valuable information for positron emission tomography/computed tomography (PET/CT)-based staging in this patient population.
Patients And Methods: Patients newly diagnosed with ENKTCL who underwent initial staging with both PET/CT and BM examination between 2013 and 2020 were retrospectively identified in two Chinese institutions.
Wheat miRNA member TaMIR1139 targets genes functional in various families and plays crucial roles in regulating plant Pi starvation tolerance. Through regulating target genes at posttranscriptional or translational level, plant miRNAs are involved in mediating diverse biological processes associated with growth, development, and responses to adverse stresses. In this study, we characterized the expression pattern and function of TaMIR1139, a miRNA member of wheat (T.
View Article and Find Full Text PDFMicroRNAs (miRNA) families act as critical regulators for plant growth, development, and responses to abiotic stresses. In this study, we characterized TaemiR408, a miRNA family member of wheat (), for the role in mediating plant responses to Pi starvation and salt stress. TaemiR408 targets six genes that encode proteins involving biochemical metabolism, microtubule organization, and signaling transduction.
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