Improvement of smile characteristics in dentofacial deformity patients following orthognathic surgery.

The purpose of this study was to investigate the effect of bimaxillary surgery on smile characteristics, including smile line, smile arc, smile index (SI), most posterior teeth displayed(MPTD), buccal corridor ratio (BCR), and smile symmetry. The study consisted of 87 patients with dentofacial deformity: Class II (30 patients), Class III (37 patients), and asymmetry (20 patients). Pearson's chi-squared test and ANOVA were used to analyze the differences in smile characteristics across the preoperative groups.

A rapid identification method for soft tissue markers of dentofacial deformities based on heatmap regression.

Objective: The purpose of this study was to construct a facial deformity dataset and a network model based on heatmap regression for the recognition of facial soft tissue landmarks to provide a basis for clinicians to perform cephalometric analysis of soft tissue.

Materials And Methods: A 34-point face marker detection model, the Back High-Resolution Network (BHR-Net), was constructed based on the heatmap regression algorithm, and a custom dataset of 1780 facial detection images for orthognathic surgery was collected. The mean normalized error (MNE) and 10% failure rate (FR10%) were used to evaluate the performance of BHR-Net, and a test set of 50 patients was used to verify the accuracy of the landmarks and their measurement indicators.

Trehalose-6-phosphate synthase 8 increases photosynthesis and seed yield in Brassica napus.

Trehalose-6-phosphate (T6P) functions as a vital proxy for assessing carbohydrate status in plants. While class II T6P synthases (TPS) do not exhibit TPS activity, they are believed to play pivotal regulatory roles in trehalose metabolism. However, their precise functions in carbon metabolism and crop yield have remained largely unknown.

Translation machinery: the basis of translational control.

Messenger RNA (mRNA) translation consists of initiation, elongation, termination, and ribosome recycling, carried out by the translation machinery, primarily including tRNAs, ribosomes, and translation factors (TrFs). Translational regulators transduce signals of growth and development, as well as biotic and abiotic stresses, to the translation machinery, where global or selective translational control occurs to modulate mRNA translation efficiency (TrE). As the basis of translational control, the translation machinery directly determines the quality and quantity of newly synthesized peptides and, ultimately, the cellular adaption.

ECT9 condensates with ECT1 and regulates plant immunity.

Mounting an efficient defense against pathogens requires RNA binding proteins (RBPs) to regulate immune mRNAs transcription, splicing, export, translation, storage, and degradation. RBPs often have multiple family members, raising the question of how they coordinate to carry out diverse cellular functions. In this study, we demonstrate that EVOLUTIONARILY CONSERVED C-TERMINAL REGION 9 (ECT9), a member of the YTH protein family in Arabidopsis, can condensate with its homolog ECT1 to control immune responses.

Oral manifestations related to malaria: A systematic review.

Objective: To generalize the oral manifestations related to malaria and discuss their clinical significance for health professionals.

Materials And Methods: The bibliographic databases of Public MEDLINE, Embase, Web of Science and Scopus were employed to retrieve publications online from January 1781 to August 2019. Original research articles, clinical trials, and case reports published in English were included.

uORFlight: a vehicle toward uORF-mediated translational regulation mechanisms in eukaryotes.

Upstream open reading frames (uORFs) are prevalent in eukaryotic mRNAs. They act as a translational control element for precisely tuning the expression of the downstream major open reading frame (mORF). uORF variation has been clearly associated with several human diseases.

Generation of Transgenic Self-Incompatible Shows a Genus-Specific Preference for Self-Incompatibility Genes.

species employ both self-compatibility and self-incompatibility systems to regulate post-pollination events. is strictly self-incompatible, while the closely related has transitioned to self-compatibility with the loss of functional -locus genes during evolution. The downstream signaling protein, ARC1, is also required for the self-incompatibility response in some and species, and its gene is deleted in the genome.

Functional Analysis of M-Locus Protein Kinase Revealed a Novel Regulatory Mechanism of Self-Incompatibility in L.

Self-incompatibility (SI) is a widespread mechanism in angiosperms that prevents inbreeding by rejecting self-pollen. However, the regulation of the SI response in is not well understood. Here, we report that the M-locus protein kinase () , the functional homolog of in , controls SI in .

Mechanism of Salt-Induced Self-Compatibility Dissected by Comparative Proteomic Analysis in L.

Self-incompatibility (SI) in plants genetically prevents self-fertilization to promote outcrossing and genetic diversity. Its hybrids in have been widely cultivated due to the propagation of SI lines by spraying a salt solution. We demonstrated that suppression of SI from edible salt solution treatment was ascribed to sodium chloride and independent of haplotypes, but it did not obviously change the expression of SIrelated genes.

Time-Course Transcriptome Analysis of Compatible and Incompatible Pollen-Stigma Interactions in L.

species exhibit both compatible and incompatible pollen-stigma interactions, however, the underlying molecular mechanisms remain largely unknown. Here, RNA-seq technology was applied in a comprehensive time-course experiment (2, 5, 10, 20, and 30 min) to explore gene expression during compatible/incompatible pollen-stigma interactions in stigma. Moderate changes of gene expression were observed both in compatible pollination (PC) and incompatible pollination (PI) within 10 min, whereas drastic changes showed up by 30 min, especially in PI.

Helitron-like transposons contributed to the mating system transition from out-crossing to self-fertilizing in polyploid Brassica napus L.

The mating system transition in polyploid Brassica napus (AACC) from out-crossing to selfing is a typical trait to differentiate it from their diploid progenitors. Elucidating the mechanism of mating system transition has profound consequences for understanding the speciation and evolution in B. napus.

Gene expression and genetic analysis reveal diverse causes of recessive self-compatibility in Brassica napus L.

Background: Brassica napus (AACC) is self-compatible, although its ancestor species Brassica rapa (AA) and Brassica oleracea (CC) are self-incompatible. Most B.napus accessions have dominant self-compatibility (SC) resulting from an insertion of 3.