Publications by authors named "Guillermo Lopez-Medina"

Coronary artery aneurysms are described as a localized dilatation that exceeds the normal diameter by 1.5 times. This is a rare condition; its incidence varies from 0.

View Article and Find Full Text PDF
Article Synopsis
  • Coronary artery aneurysms are rare localized dilations of coronary arteries, with incidences between 0.3% and 5.3%, and are classified as giant if they exceed 4 times the normal diameter.
  • They are often linked to atherosclerosis, particularly affecting individuals in their 60s and 70s, and primarily present with symptoms of ischemic heart disease.
  • Treatment options vary and lack consensus, ranging from medical to surgical interventions, as illustrated by a case involving a patient with a giant right coronary artery aneurysm and associated complications.
View Article and Find Full Text PDF

Eosinophilic gastroenteritis is considered an uncommon disease with a low incidence rate that remains as a diagnostic challenge for the clinician, in spite of the fact that seventy years have passed since its original description. Hereby we present the case of a 29-year-old male without history of allergies who was evaluated for unspecific gastrointestinal symptoms, without relevant findings on physical examination and presenting an initial complete blood count (CBC) with severe eosinophilia. The patient was evaluated and the diagnosis of eosinophilic gastroenteritis was confirmed by histopathological findings.

View Article and Find Full Text PDF

The finding of gas within the gastric wall is not a disease by itself, rather than a sign of an underlying condition which could be systemic or gastric. We present the case of a woman identified with gastric emphysema secondary to the administration of high doses of steroids, with the purpose of differentiating emphysematous gastritis versus gastric emphysema due to the divergent prognostic implications. Gastric emphysema entails a more benign course, opposed to emphysematous gastritis which often presents as an acute abdomen and carries a worse prognosis.

View Article and Find Full Text PDF

Osteoporosis is characterized by low bone mineral density (BMD). One of the most important factors that influence BMD is the genetic contribution. The collagen type 1 alpha 1 (COL1A1) and the JAGGED (JAG1) have been investigated in relation to BMD.

View Article and Find Full Text PDF
Article Synopsis
  • This study examines the relationship between genetic variations in the TNFRSF11B gene and bone mineral density (BMD) in postmenopausal Mexican Mestizo women.
  • A total of 750 women participated, with BMD assessed at the hip and lumbar spine, while three specific single-nucleotide polymorphisms (SNPs) were analyzed.
  • The research found that while individual SNPs did not show significant differences, a specific haplotype (A-G-T) was linked to variations in femoral neck BMD, suggesting haplotypes may serve as better genetic markers for BMD variations.
View Article and Find Full Text PDF

Objective: Considering that the Mexican mestizo population seems to be the result of a genetic admixture, we proposed that further research is needed to evaluate the role of ethnicity in conjunction with health-related factors to better understand ethnic differences in bone mineral density (BMD). The aim of this study was to analyze several risk factors related to the development of osteoporosis in postmenopausal Mexican mestizo women.

Methods: We included 567 postmenopausal Mexican mestizo women.

View Article and Find Full Text PDF