Nutritional status at age 1 year in patients born with esophageal atresia: A population-based, prospective cohort study.

Objective: Despite recent progress in caring for patients born with esophageal atresia (EA), undernutrition and stunting remain common. Our study objective was to assess nutritional status in the first year after birth with EA and to identify factors associated with growth failure.

Study Design: We conducted a population-based study of all infants born in France with EA between 2010 and 2016.

Different Fecal Microbiota in Hirschsprung's Patients With and Without Associated Enterocolitis.

Background And Objectives: Patients with Hirschsprung's disease are at risk of developing Hirschsprung-associated enterocolitis, especially in the first 2 years of life. The pathophysiology of this inflammatory disease remains unclear, and intestinal dysbiosis has been proposed in the last decade. The primary objective of this study was to evaluate in a large cohort if Hirschsprung-associated enterocolitis was associated with alterations of fecal bacterial composition compared with HD without enterocolitis in different age groups.

Esophageal Atresia and Respiratory Morbidity.

Background And Objectives: Respiratory diseases are common in children with esophageal atresia (EA), leading to increased morbidity and mortality in the first year. The primary study objective was to identify the factors associated with readmissions for respiratory causes in the first year in EA children.

Methods: A population-based study.

Risk Factors of Early Mortality and Morbidity in Esophageal Atresia with Distal Tracheoesophageal Fistula: A Population-Based Cohort Study.

Objective: To identify the risk factors for early mortality and morbidity in a population with distal esophageal atresia (EA)-tracheoesophageal fistula.

Study Design: Cohort study from a national register. Main outcomes and measures included early mortality, hospital length of stay (LoS), need for nutritional support at 1 year of age as a proxy measure of morbidity, and complications during the first year of life.

Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung's disease.

In Hirschsprung's disease (HSCR), postoperative course remains unpredictable. Our aim was to define predictive factors of the main postoperative complications: obstructive symptoms (OS) and Hirschsprung-associated enterocolitis (HAEC). In this prospective multicentre cohort study, samples of resected bowel were collected at time of surgery in 18 neonates with short-segment HSCR in tertiary care hospitals.

Management of lower urinary tract fibroepithelial polyps in children.

Introduction: Fibroepithelial polyps (FEP) of the lower urinary tract are relatively common in adults but rare in children, with fewer than 250 cases reported in the literature to date.

Objective: The aim of this study was to address the experience of FEP management in children.

Study Design: A retrospective multicenter review was undertaken in children with defined FEP of the lower urinary tract managed between 2008 and 2018.

One-Year Outcome for Congenital Diaphragmatic Hernia: Results From the French National Register.

Objective: To evaluate the status of congenital diaphragmatic hernia (CDH) management in France and to assess predictors of adverse outcomes.

Study Design: We reviewed the first-year outcome of all cases of CDH reported to the French National Register in 2011.

Results: A total of 158 cases were included.

What prenatal ultrasound features are predictable of complex or vanishing gastroschisis? A retrospective study.

Objective: To evaluate prenatal ultrasound parameters as prognostic factors for complex and vanishing gastroschisis.

Methods: Retrospective multicentre study of 200 gastroschisis over 13 years (2000-2013). Collection of prenatal ultrasound evaluation on maternal and fetal growth parameters, intra- and extra-abdominal bowel and stomach dilation, abdominal wall defect diameter and changes in bowel appearance.

DICER1 pleuropulmonary blastoma familial tumour predisposition syndrome: What the paediatric urologist needs to know.

Introduction: Germline-inactivating DICER1 mutations are responsible of a familial tumour susceptibility syndrome with an increased risk of tumours, mainly pleuropulmonary blastoma (PPB). DICER1 mutations also cause a range of other tumours, some of them in urogenital organs (cystic nephroma [CN], ovarian sex cord-stromal tumours, bladder and cervix embryonal rhabdomyosarcoma [ERMS]).

Objective: The aim was to clarify the range of urogenital phenotypes associated with DICER1 mutations and to give practical course of action to paediatric urologist that are exposed to DICER1-related conditions.

Epidermal healing in burns: autologous keratinocyte transplantation as a standard procedure: update and perspective.

Background: Treatment of burned patients is a tricky clinical problem not only because of the extent of the physiologic abnormalities but also because of the limited area of normal skin available.

Methods: Literature indexed in the National Center (PubMed) has been reviewed using combinations of key words (burns, children, skin graft, tissue engineering, and keratinocyte grafts). Articles investigating the association between burns and graft therapeutic modalities have been considered.

Study of proliferation and 3D epidermal reconstruction from foreskin, auricular and trunk keratinocytes in children.

Objective: Severe burns in children are conventionally treated with split-thickness skin autografts or epidermal sheets. An alternative approach is to graft isolated keratinocytes. We evaluated foreskin and other anatomic sites as donor sources for autologous keratinocyte graft in children.

Esophageal atresia: data from a national cohort.

Purpose: A prospective national register was established in 2008 to record all new cases of live-birth newborns with esophageal atresia (EA). This epidemiological survey was recommended as part of a national rare diseases plan.

Methods: All 38 national centers treating EA participated by completing for each patient at first discharge a questionnaire validated by a national committee of experts.

Foreskin-isolated keratinocytes provide successful extemporaneous autologous paediatric skin grafts.

Severe burns in children are conventionally treated with split-thickness skin autografts or epidermal sheets. However, neither early complete healing nor quality of epithelialization is satisfactory. An alternative approach is to graft isolated keratinocytes.

Infantile hypertrophic pyloric stenosis: are viruses involved?

Infantile hypertrophic pyloric stenosis (IHPS) is characterized by abnormal thickening of the internal circular muscle layer. IHPS is known to be due to a combination of genetic and environmental factors, but its precise causes and pathophysiology are poorly understood. The objective of the study is to determine the prevalence of the principal viruses targeting the respiratory and digestive tracts in children with IHPS.

Growth in infants in the first two years of life after neonatal repair for unilateral cleft lip and palate.

Objective: To evaluate the growth during the first two years of life in infants after unilateral cleft lip and palate neonatal repair.

Method: All mature infants with nonsyndromic unilateral cleft lip and palate (NSUCLP) born between 2004 and 2007 were included. Information concerning growth was collected.

Solitary intestinal fibromatosis associated with congenital ileal atresia.

We report for the first time an association between congenital solitary intestinal fibromatosis and intestinal atresia. The spindle cell proliferation showed a high apoptotic index contrasting with a low proliferation rate, suggesting that the tumor may have undergone focal and spontaneous regression, leading to intestinal atresia.

Early repair for infants with cleft lip and nose.

Objective: To study the results 10 years after early surgical cleft lip and nose repair.

Patients And Methods: We present the outcome of 123 early cleft lip repairs whose condition was managed in a multidisciplinary team according to a strict protocol. We give the observation results of operations of a single surgeon's neonatal surgery over a 10-year period in term of aesthetic assessments and dental arch relationships.

Surgical treatment of haemangioma in infants.

Haemangiomas usually can be identified by their clinical course. They are characterised by presentation at birth or shortly thereafter, and a rapid proliferative phase over the first 12 months. The haemangioma then usually stabilises and slowly involutes over a period of 5-7 years.

[Vesicoureteral reflux: diagnosis and management in children].

Objective: Based on a retrospective study of children followed for vesicoureteric reflux, the authors evaluated the role of antenatal diagnosis in the detection and global management of the most frequent uropathy observed in children.

Materials And Methods: The case files of 180 children followed for reflux over a 4-year period were reviewed. The diagnosis of reflux was based on retrograde cystography.

[Laparoscopic treatment of the nonpalpable testis. Results].

Objective: The purpose of laparoscopy in the management of the non palpable testis is to provide information regarding testicular presence and location to facilitate overall surgical management.

Materials And Methods: We report our experience with laparoscopic orchiopexy to treat 39 nonpalpable testes in 32 patients, patient age ranged from 2.3 years to 14 years (average 4.