Publications by authors named "Guillaume Bendavid"
Article Synopsis
- Asthma is linked to airway inflammation and structural changes, and the role of ADAM28, a protein expressed in certain immune cells, in this condition is being explored.* -
- In experiments with mice, those lacking ADAM28 showed less airway responsiveness and reduced airway remodeling features, suggesting ADAM28 exacerbates asthma symptoms.* -
- The study provides evidence that ADAM28 influences airway remodeling and the immune response in asthma, indicating its potential importance in asthma pathophysiology.*
Previous studies have linked cancer cell-associated ADAM28 expression with tumor progression and metastatic dissemination. However, the role of host-derived ADAM28 in cancer dissemination processes remains unclear. Genetically engineered-mice fully deficient for ADAM28 unexpectedly display increased lung colonization by pulmonary, melanoma or breast tumor cells.
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