Haemophagocytic lymphohistiocytosis following a COVID-19 infection: case report.

The case of a 57-year-old male patient with jaundice, high-grade fever, and upper abdominal pain who was recovering from a mild coronavirus disease-19 (COVID-19) infection is reported. Laboratory analysis showed liver injury with high levels of AST and ALT, as well as an elevated serum ferritin level. The patient underwent a bone marrow biopsy which showed features of hemophagocytic lymphohistiocytosis (HLH), a systemic syndrome caused by immune activation.

What happens to intolerant, relapsed or refractory chronic myeloid leukemia patients without access to clinical trials?

Objective: To assess clinical outcomes of intolerant, relapsed or refractory patients who could not be treated with new tyrosine kinase inhibitors or experimental therapies.

Methods: A retrospective cohort of 90 chronic myeloid leukemia patients in all phases of the disease treated with imatinib mesylate as their first TKI therapy, and with dasatinib or nilotinib as the next line of therapy. We evaluated clinical outcomes of these patients, with special focus on the group that needed more than two therapy lines.

Reliability and internal consistency of questionnaire for evaluating weight cycling in Southern Brazil.

Aims And Objectives: To determine the reliability and internal consistency of a questionnaire that was designed to assess weight cycling.

Background: A large part of the obese population attempt to lose weight. Of those who had lost at least 10% of their initial weight, 33·5% regained weight.

Fungus ball of the paranasal sinuses: Report of two cases and literature review.

Introduction:  Fungal ball of the sinuses is a not invasive infection that if characterizes for its chronicity, being the majority related with previous endodontic treatment. Affect mainly the breasts to maxillary; even so all the breasts can be involved. The main etiological agent is the Aspergillus spp.