The present study aimed to evaluate the results of the intraoperative topical use of a human fibrin sealant free of clot-stabilizing agents in total knee arthroplasties (TKAs), looking for differences between groups regarding blood loss, transfusion requirement, length of hospital stay, pain perception, range of motion (ROM), and incidence of complications. We have analyzed prospectively an intervention group with 32 patients (Sealant) and a control group with 31 patients (Control) with symptomatic knee osteoarthritis who underwent TKA. The results were similar between the groups regarding visible blood loss in the drain in 24 hours (Control, 276.
View Article and Find Full Text PDFObjective: Evaluate the efficacy of tranexamic acid in reducing bleeding in patients undergoing total knee arthroplasty.
Methods: 101 patients were randomized into two groups: the tranexamic acid group ( = 51) and the placebo group ( = 50). Patients were compared regarding the following parameters: reduction of hemoglobin, total estimated blood loss, drain output, and postoperative blood transfusion rate.