Publications by authors named "Guilherme Mariante-Neto"

Alcohol consumption accounts for 3.8% of annual global mortality worldwide, and the majority of these deaths are due to alcoholic liver disease (ALD), mainly alcoholic cirrhosis. ALD is one of the most common indications for liver transplantation (LT).

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Background: The model for end-stage liver disease (MELD) is based on objective variables, including serum creatinine (SCr). This study assesses the influence of skin color on MELD scores calculated using SCr or corrected creatinine (CrC) in female candidates for liver transplantation (LTx).

Methods: White and black women were eligible.

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Article Synopsis
  • A systematic bias in the allocation of liver transplants has been identified, affecting women due to standard creatinine measurements, which underestimate their renal function compared to men.
  • Researchers studied 639 female and male candidates for liver transplantation and applied the MDRD formula to adjust creatinine levels for gender.
  • The study found that while correcting creatinine levels increased MELD scores for women slightly, both genders had similar survival rates and chances of receiving a transplant within 3 and 6 months, indicating that the correction did not enhance the predictive accuracy of the MELD score.
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Background: Patients infected with the human immunodeficiency virus (HIV) have generally been excluded from consideration for liver transplantation. Recent advances in the management and prognosis of these patients suggest that this policy must be reevaluated.

Aim: To identify the current position of Brazilian transplant centers concerning liver transplantation in asymptomatic HIV-infected patients with end-stage liver disease.

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Objective: To evaluate clinical and evolutive characteristics of patients admitted in an intensive care unit after cardiopulmonary resuscitation, identifying prognostic survival factors.

Methods: A retrospective study of 136 patients admitted between 1995 and 1999 to an intensive care unit, evaluating clinical conditions, mechanisms and causes of cardiopulmonary arrest, and their relation to hospital mortality.

Results: A 76% mortality rate independent of age and sex was observed.

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