Publications by authors named "Guilherme L S Meira"
Inhibition by Marine Algae of Chikungunya Virus Isolated From Patients in a Recent Disease Outbreak in Rio de Janeiro.
Front Microbiol
October 2019
Article Synopsis
- Chikungunya virus (CHIKV) is a re-emerging disease with no specific antiviral treatment, posing a serious public health threat.
- Blood samples from patients displayed CHIKV symptoms, leading to the successful isolation of 3 virus strains which were characterized through sequencing to assess their similarity to recent Brazilian outbreaks.
- Seaweed extracts showed significant antiviral effects against CHIKV, with specific extracts demonstrating low toxicity and optimal inhibition when added to infected cells within 16 hours, suggesting their potential as therapeutic agents against the virus.
Article Synopsis
- * The study analyzed the complete genome of 12 YFV samples from various sources during the 2017 epidemic, revealing they belong to a specific lineage (1E) that had been circulating months before its official detection.
- * The findings highlight unique amino acid changes in the virus, indicating its spread into densely populated areas and offering valuable insights for guiding public health measures and further research on the virus's evolution.
During 2014-2016, we conducted mosquito-based Zika virus surveillance in Rio de Janeiro, Brazil. Results suggest that Zika virus was probably introduced into the area during May-November 2013 via multiple in-country sources. Furthermore, our results strengthen the hypothesis that Zika virus in the Americas originated in Brazil during October 2012-May 2013.
View Article and Find Full Text PDFKlebsiella pneumoniae is a pathogen frequently associated with antibiotic-resistant nosocomial infections. Here, we describe the genome of KP-Rio/2015, a novel phage of K. pneumoniae belonging to the family Podoviridae.
View Article and Find Full Text PDFCell division in bacteria is carried out by an elaborate molecular machine composed of more than a dozen proteins and known as the divisome. Here we describe the characterization of a new divisome protein in Bacillus subtilis called YpsB. Sequence comparisons and phylogentic analysis demonstrated that YpsB is a paralog of the division site selection protein DivIVA.
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