Publications by authors named "Guilherme Francisquini Rocha"
Purinergic Signal
October 2024
Article Synopsis
- Purine nucleotides and nucleosides are crucial in various diseases, especially in tumor growth, with ATP promoting tumor receptor activation and adenosine acting as an immunosuppressant.
- This study explores how ATP and its metabolites, along with specific receptors, impact primary central nervous system tumors and their progression.
- The results suggest that the purinergic system's role in tumors can vary, acting as either a promoter or inhibitor of tumor growth, depending on receptor density and the surrounding environment, highlighting ATP's significance in cancer development.*
