Publications by authors named "Guilherme A S Silva"
Healthcare workers exposed to COVID-19 patients present an inflammatory status and Th2/Th17/Th22 immune profile: findings from before vaccine application in Brazil.
An Acad Bras Cienc
June 2023
Article Synopsis
- Healthcare workers are at a higher risk of SARS-CoV-2 infection due to their exposure to infected patients, necessitating a study of their clinical and immunological status.
- A study involving 50 healthcare professionals in Brazil revealed that most participants were women over 50 years old working as nursing technicians, with around 56% testing positive for previous COVID-19 infection.
- Immunological findings indicated signs of light inflammation and a distinct immune response in positive workers, highlighting the need for further research on the long-term effects of continuous virus exposure in this group.
The severe consequences of ZIKV infection and its emergence and re-emergence in several countries have boosted vaccines' development. Yeasts such as Pichia pastoris has been widely employed as antigen carriers for immunization against infectious agents. Components of the yeast cell wall have immunostimulatory properties, and recombinant antigens can be anchored to the cell surface to enhance the presentation to the immune system.
View Article and Find Full Text PDFCoronavirus is associated with several infectious diseases that cause outbreaks in humans, such as SARS in 2002-2003 and MERS in 2012. In December 2019, COVID-19, promoted by the SARS-CoV-2 virus, was first reported in Wuhan (China) as a new coronavirus disease. This outbreak quickly reached a pandemic status, affecting at least 185 countries and territories to date on all continents.
View Article and Find Full Text PDFProcedures of measurement of the body mass in children by community health agents in Macaé, Rio de Janeiro, Brazil, 2010-2011.
Epidemiol Serv Saude
December 2018
Objective: to describe the measurement process of the body mass in children under seven years old, assisted by community health agents in primary health care units of the Family Health Strategy, in Macaé-RJ, Brazil.
Methods: a descriptive study with community health agents who measured the body mass of children, from August 2010 to August 2011.
Results: ¾ (n=65) of the community health agents from Macaé Primary Health Care were observed in 196 measurements; in 66.