Global burden and attributable risk factors of inflammatory cardiomyopathy and myocarditis from 1990 to 2019.

Background: Our understanding of the global burden distribution of inflammatory cardiomyopathy and myocarditis is very limited.

Objective: To comprehensively assess the global burden distribution and attributable risk factors of inflammatory cardiomyopathy and myocarditis from 1990 to 2019.

Methods: We extracted the data on death, disability-adjusted life years (DALY), and age-standardized rate (ASR) of inflammatory cardiomyopathy and myocarditis from the 2019 Global Burden of Disease (GBD) study, including the comprehensive data and the data classified by age/sex.

Stage IV ovarian cancer prognosis nomogram and analysis of racial differences: A study based on the SEER database.

Purpose: Stage IV ovarian cancer is a tumor with a poor prognosis and lacks prognostic models. This study constructed and validated a model to predict overall survival (OS) in patients with newly diagnosed stage IV ovarian cancer.

Methods: The data of this study were extracted from SEER database.

The Alfalfa-inpatient-CAT assessment model: a thrombotic risk assessment model for inpatient cancer patients.

Purpose: To construct a venous thromboembolism (VTE) risk assessment model specifically for inpatients with cancer.

Method: Patients were included according to the inclusion criteria. Univariate and multivariate analyses of all variables were included to develop a VTE risk assessment model applicable to the derivation cohort.

Identification and functional analysis of floral terpene synthase genes in Curcuma alismatifolia.

CaTPS2 and CaTPS3 were significantly expressed in flowers of Curcuma alismatifolia 'Shadow' and demonstrated bifunctional enzyme activity, CaTPS2 generated linalool and nerolidol as products, and CaTPS3 catalyzed β-myrcene and β-farnesene formation. This study presents the discovery and functional characterization of floral terpene synthase (TPS) genes in Curcuma alismatifolia 'Shadow', a cultivar renowned for its unique fragrance. Addressing the gap in understanding the genetic basis of floral scent in this species, we identified eight TPS genes through comprehensive transcriptome sequencing.

Efficacy and safety of dabigatran and rivaroxaban in atrial fibrillation patients with impaired liver function: a multicenter retrospective cohort study.

Background: The efficacy and safety of direct oral anticoagulants (DOACs) in atrial fibrillation (AF) patients with impaired liver function (ILF) have not been sufficiently studied. The aim of this study was to evaluate the efficacy and safety of DOACs for stroke prevention in patients with AF and ILF.

Method: This study was based on data from 15 centers in China, including 4,982 AF patients.

Distribution and mobility of copper, zinc and lead in plant-sediment systems of Quanzhou Bay estuary, China.

The distribution, mobility and potential risks of Cu, Zn, and Pb in four typical plant-sediment co-systems of the Quanzhou Bay estuary wetland in southeast China were investigated using a sequential extraction procedure. The results show that the sediments were moderately or heavily contaminated with Zn and Pb in all four plant communities, and the plant-sediment systems could act as a sink for the heavy metals. In all investigated sediments, only a small proportion of measured heavy metals were distributed in exchangeable fraction and carbonate fraction, while the reducible fraction contained the highest amount of Zn and Pb of the total readily bioavailable fractions, and the oxidizable fraction exhibited a higher retention capacity for Zn and Cu, but lower for Pb.