Oncolytic viruses (OVs) have emerged as effective gene therapy and immunotherapy drugs. As an important gene delivery platform, the integration of exogenous genes into OVs has become a novel path for the advancement of OV therapy, while the herpes simplex virus type 1 (HSV-1) is the most commonly used. However, the current mode of administration of HSV-1 oncolytic virus is mainly based on the tumor in situ injection, which limits the application of such OV drugs to a certain extent.
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February 2023
Many restoration methods use the low-rank constraint of high-dimensional image signals to recover corrupted images. These signals are usually represented by tensors, which can maintain their inherent relevance. The image of this simple tensor presentation has a certain low-rank property, but does not have a strong low-rank property.
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