[Fonction de l'ARNnc exosomal HEIH dans le carcinome hépatocellulaire associé au virus de l'hépatite B].

Long non-coding RNA-HEIH (lncRNA-HEIH) is a potential biomarker for patients with hepatocellular carcinoma (HCC), but exosomal lncRNA-HEIH in patients with hepatitis B virus-associated HCC (B-HCC) is unclear. This study aimed to investigate the expression of exosomal lncRNA-HEIH in B-HCC patients and explore its clinical significance. We collected blood samples from 60 B-HCC patients, 60 non-hepatitis virus-associated HCC (N-HCC) patients, and 50 healthy volunteers.

Lack of PPAR/-Inactivated SGK-1 Is Implicated in Liver Carcinogenesis.

Objective: The present study examined the role of PPAR/ in hepatocellular carcinoma (HCC).

Methods: The effect of PPAR/ on HCC development was analyzed using PPAR/-overexpressed liver cancer cells and PPAR/-knockout mouse models.

Results: PPAR/ mice were susceptible to diethylnitrosamine- (DEN-) induced HCC (87.