Genome-Wide Identification, Characterization, and Expression Analysis of the Gene Family in .

NAC proteins play an essential role in the growth and development of litchi, especially during reproductive development. However, a comprehensive analysis of the litchi gene family is currently absent. Based on information from the litchi genome, we found that the 112 NAC genes of litchi show an uneven distribution on the chromosomes.

Brachial-ankle pulse wave velocity as a risk factor for high body fat mediated by blood pressure.

Background: Brachial-ankle pulse wave velocity (baPWV) is an important clinical indicator of aortic stiffness and a risk predictor of cardiovascular disease and associated with obesity. However, whether body mass index (BMI) is associated with baPWV remains controversial. In our study, body fat-related indicators, including BMI, body fat rate (BFR), body fat volume (BFV), waist circumference (WC) were examined from healthy volunteers.

Role of eotaxin-1/CCL11 in sepsis-induced myocardial injury in elderly patients.

Myocardial injury is a serious complication of sepsis. The present study aimed to identify potential biomarkers of sepsis-induced myocardial injury. Differentially expressed genes (DEGs) in patients and mice with sepsis-induced myocardial injury were identified via bioinformatic analysis.

Trp fluorescence reveals an activation-dependent cation-pi interaction in the Switch II region of Galphai proteins.

Crystal structures of Galpha(i) (and closely related family member Galpha(t)) reveal much of what we currently know about G protein structure, including changes which occur in Switch regions. Galpha(t) exhibits a low rate of basal (uncatalyzed) nucleotide exchange and an ordered Switch II region in the GDP-bound state, unlike Galpha(i), which exhibits higher basal exchange and a disordered Switch II region in Galpha(i)GDP structures. Using purified Galpha(i) and Galpha(t), we examined the intrinsic tryptophan fluorescence of these proteins, which reports conformational changes associated with activation and deactivation of Galpha proteins.

Receptor-mediated changes at the myristoylated amino terminus of Galpha(il) proteins.

G protein-coupled receptors (GPCRs) catalyze nucleotide release in heterotrimeric G proteins, the slow step in G protein activation. G i/o family proteins are permanently, cotranslationally myristoylated at the extreme amino terminus. While myristoylation of the amino terminus has long been known to aid in anchoring G i proteins to the membrane, the role of myristoylation with regard to interaction with activated receptors is not known.

[Analysis on the long-term curative effect of endoscopic sinus surgery].

Objective: To analyze the long-term curative effect of endoscopic sinus surgery.

Method: One hundred and twenty-eight cases (180 sides) of chronic sinusitis and nasal polyps were treated with FESS, 80 side (64 cases) were elected randomly to deal with the anatomical variation of middle and inferior turbinate and nasal septum during the operation (rectification group), comparing the curative effects with other 100 sides (64 cases) (contrast group).

Result: Following up survey from 12 months to 24 months postoperatively, the curative effect in the rectification group was better than that in the contrast group.