Perioperative change trajectories and predictors of swallowing function and swallowing-related quality of life in patients with oral cancer: a longitudinal observational study.

Objective: To determine change trajectories and predictors of swallowing function and swallowing-related quality of life (QoL) in perioperative patients with oral cancer.

Design: Longitudinal observational study.

Setting: A tertiary cancer hospital in Hunan Province, China.

Perioperative nutritional risk and its influencing factors in patients with oral cancer: a longitudinal study.

Introduction: We aimed to investigate the nutritional risk status and dynamic changes in patients with perioperative oral cancer at different stages and analyze the factors influencing nutritional risk and the correlation among body mass index, nutrition-related symptoms, and nutritional risk.

Methods: In total, 198 patients with oral cancer who were hospitalized in the Head & Neck Surgery Departments of a tertiary cancer hospital in Hunan Province, China, from May 2020 to January 2021, were selected as participants. The Nutritional Risk Screening 2002 scale and Head and Neck Patient Symptom Checklist were used to assess patients on admission day, 7 days post-surgery, and 1 month post-discharge.

Effect Analysis of Positive Molecular Therapy in Surgical Nursing Based on Data Transformation Analysis.

This paper briefly introduces the concept, classification, and mechanism of action of positive thinking therapy; reviews the application and research progress of positive thinking therapy in perioperative care of surgical patients at home and abroad; presents the shortcomings and defects in the development; and aims to provide intervention, reference, and basis for the development of positive thinking therapy in perioperative care of surgical patients. One hundred and eight patients are undergoing PCI surgery in our cardiology department; 50 patients undergoing percutaneous coronary intervention were selected as the control group, and 58 patients undergoing percutaneous coronary intervention were selected as the observation group. Traditional health education was employed in the control group, while empowerment education based on timing theory was used in the observation group.

Perioperative symptom burden and its influencing factors in patients with oral cancer: A longitudinal study.

Objective: The aim of this study was to identify the symptom burden of perioperative oral cancer patients, its trajectory, and the factors influencing it.

Methods: A longitudinal, repeated measures design with consecutively identified sampling was used to recruit oral cancer patients scheduled for surgical treatment. Data collected included sociodemographic and clinical information, nutritional risk by the Nutritional Risk Screening 2002, and symptom burden by M.

Characteristics of subsurface chlorophyll maxima during the boreal summer in the South China Sea with respect to environmental properties.

Characterizing the vertical distribution of chlorophyll a in the water column in each oceanic region is crucial for accurate assessment of depth-integrated phytoplankton biomass. In this study, the characteristics of the subsurface chlorophyll maximum (SCM) in the South China Sea (SCS) during the boreal summer were investigated by using bio-optical and hydrological data collected during four cruises from 2008 to 2015. During the boreal summer, a well-developed SCM layer was found to be a prominent feature in the SCS, with the thickness, depth, and magnitude of the SCM exhibiting large spatial variability.

Assessing responses of phytoplankton to consecutive typhoons by combining Argo, remote sensing and numerical simulation data.

Typhoons can affect various hydrodynamic processes, such as upwelling, vertical mixing, and entrainment, which in turn influence the growth and redistribution of phytoplankton. In this study, responses of phytoplankton to consecutive typhoons Barijat and Mangkhut in summer 2018 in the northern South China Sea (NSCS) were investigated through combining remote sensing, numerical simulation, and Argo profile data. Variations of physical and biological properties induced by Barijat and Mangkhut over the study region were observed.

Ultraviolet light-emitting diode irradiation induces reactive oxygen species production and mitochondrial membrane potential reduction in HL-60 cells.

Objective: Ultraviolet light-emitting diode (UV LED) irradiation at 280 nm has been confirmed to induce apoptosis in cultured HL-60 cells, but the underlying mechanisms remain unclear. This study aimed to investigate the effects of 280 nm UV LED irradiation on reactive oxygen species (ROS) production and mitochondrial membrane potential (MMP) in HL-60 cells.

Methods: HL-60 cells were irradiated with 0, 8, 15, or 30 J/m of 280 nm UV LED and incubated for 2 hours.

A Bacterium Isolated From Soil in a Karst Rocky Desertification Region Has Efficient Phosphate-Solubilizing and Plant Growth-Promoting Ability.

Phosphorus in the soil accessible to plants can easily be combined with calcium ion, the content of which is high in karst rocky desertification (KRD) regions, thereby resulting in a low utilization efficiency of phosphorus. The application of phosphate-solubilizing bacteria (PSB) from the KRD region would facilitate enhanced phosphate availability in the soil. In the present study, the strains belonging to , , and with efficient phosphate-solubilizing ability were isolated from fruit tree rhizosphere soils in KRD regions.

Intrinsic Abnormalities of Keratinocytes Initiate Skin Inflammation through the IL-23/T17 Axis in a MALT1-Dependent Manner.

Increasing evidence has supported the crucial role of CARD14 in the pathogenesis of psoriasis, whereas the precise cellular signaling involved in skin physiopathology remains poorly understood. In this article, we show that neither genetic ablation of nor elimination of T cells was sufficient to restrain the skin inflammation in a CARD14-E138A-mutation-induced psoriasis-like mouse model, whereas depletion of , which extremely blocked the IL-23/T17 axis, was more effective. Targeting CBM complex by conditional deletion of MALT1 or BCL10 in keratinocytes abrogated both the cutaneous and systemic inflammation of heterozygous mice.

Evaluating semi-analytical algorithms for estimating inherent optical properties in the South China Sea.

Using large amounts of bio-optical data collected in the South China Sea (SCS) from 2003 to 2016, this study checks the consistency between well-known semi-analytical algorithms (SAAs)-the quasi-analytical algorithm (QAA) and the default generalized inherent optical property (GIOP-DC)-in retrieving the non-water absorption coefficient (a(λ)), phytoplankton absorption coefficient (a(λ)) and particulate backscattering coefficient (b(λ)) from remote-sensing reflectance (R(λ)) data at 412, 443, 490, 531, and 555 nm. The samples from the SCS are further separated into oligotrophic and mesotrophic water types for the comparison of the SAAs. Several findings are made: First, the values of an(λ) derived from the two SAAs deliver similar performance, with R values ranging from 0.

Estimation of suspended particulate matter in turbid coastal waters: application to hyperspectral satellite imagery.

An empirical algorithm is proposed to estimate suspended particulate matter (SPM) ranging from 0.675 to 25.7 mg L in the turbid Pearl River estuary (PRE).

Ube2s stabilizes β-Catenin through K11-linked polyubiquitination to promote mesendoderm specification and colorectal cancer development.

The canonical Wnt/β-Catenin signaling pathway is widely involved in regulating diverse biological processes. Dysregulation of the pathway results in severe consequences, such as developmental defects and malignant cancers. Here, we identified Ube2s as a novel activator of the Wnt/β-Catenin signaling pathway.

Linear ubiquitin chain induces apoptosis and inhibits tumor growth.

Ubiquitination of proliferating cell nuclear antigen (PCNA) plays an important role in DNA damage response. Ectopic expression of PCNA fused at either terminus with ubiquitin (Ub) lacking two C-terminal glycine residues induces translesion DNA synthesis which resembles synthesis mediated by PCNA monoubiquitination. PCNA fused with Ub containing the C-terminal Gly residues at the C-terminus can be further polyubiquitinated in a Gly-dependent manner, which inhibits cell proliferation and induces ATR-dependent replication checkpoint.

Uev1A facilitates osteosarcoma differentiation by promoting Smurf1-mediated Smad1 ubiquitination and degradation.

Malignant bone tumor osteosarcoma (OS) displays high metastasis incidence and poor prognosis. Its stem cell properties could serve to explain tumor recurrence and resistance to conventional treatments. In this study, we identified UEV1A as a novel suppressor of OS.

Rev7, the regulatory subunit of Polζ, undergoes UV-induced and Cul4-dependent degradation.

In eukaryotic cells, Rev7 interacts with Rev3 and functions as a regulatory subunit of Polζ, a translesion DNA synthesis (TLS) polymerase. In addition to its role in TLS, mammalian Rev7, also known as Mad2B/Mad2L2, participates in multiple cellular activities including cell cycle progression and double-strand break repair through its interaction with several proteins. Here we show that in mammalian cells, Rev7 undergoes ubiquitin/proteasome-mediated degradation upon UV irradiation in a time-dependent manner.

Evaluation of Off-Hour Emergency Care in Acute Ischemic Stroke: Results from the China National Stroke Registry.

Background And Purpose: The quality of after-hour emergency care of patients with acute ischemic stroke is debatable. We therefore, sought to analyze the performance measures, quality of care and clinical outcomes in these patients admitted during off-hours.

Methods: Our study included 4493 patients from a selected cohort of patients admitted to the hospitals with ischemic stroke in the China National Stroke Registry (CNSR) from September 2007 to August 2008.

[Protective effect of Astragalus polysaccharide on MRC-5 cells from oxidative damage induced by hydrogen peroxide].

Objective: To investigate the effects of Astragalus polysaccharide (APS) on the expressions of apurinic/apyrimidinic endonuclease/redox factor-1 (APE/Ref-1) and thioredoxin (TRX) in MRC-5 human embryo lung fibroblasts induced by hydrogen peroxide (H2O2) and explore the mechanism of APS protecting MRC-5 cells from oxidative damage.

Methods: The MRC-5 cells were randomly divided into groups: the normal control group, groups induced by H2O2 of different concentrations, groups treated with 200, 400, 800 mg/L APS. The inhibitory rate of cell proliferation in H2O2-induced MRC-5 cells was measured by MTT assay to make sure the successful establishment of oxidative damage model.

[Experiment on pruning of Cistanche deserticola inoculated in artificial Haloxylon ammodendron forest].

At present, the objective of cutting and pruning Cistanche deserticola is to harvest in successive years and enhance the harvesting yield and quality of C. deserticola in the process of the artificial cultivating C. deserticola.

Satellite-observed variability of phytoplankton size classes associated with a cold eddy in the South China Sea.

Ocean-color remote sensing has been used as a tool to detect phytoplankton size classes (PSCs). In this study, a three-component model of PSC was reparameterized using seven years of pigment measurements acquired in the South China Sea (SCS). The model was then used to infer PSC in a cyclonic eddy which was observed west of Luzon Island from SeaWiFS chlorophyll-a (chla) and sea-surface height anomaly (SSHA) products.

[Variations in the optical absorption and attenuation properties of cultured phytoplankton and their relationships with cell size].

The spectral absorption and attenuation coefficients of 16 phytoplankton species were measured in the laboratory using acs instrument. Ancillary measurements included particle size distribution and chlorophyll a concentration (Chl a). The results indicated that both algal cell size and Chl a were the two major factors dominating the magnitudes of the spectral absorption and attenuation coefficients.

Variations in the optical scattering properties of phytoplankton cultures.

The scattering and backscattering coefficients of 15 phytoplankton species were determined in the laboratory using the acs and BB9 instruments. The spectral variability of scattering properties was investigated and the homogenous sphere model based on Mie theory was also evaluated. The scattering efficiencies at 510 nm varied from 1.

Variation of particulate organic carbon and its relationship with bio-optical properties during a phytoplankton bloom in the Pearl River estuary.

In this study, variations in the particulate organic carbon (POC) were monitored during a phytoplankton bloom event, and the corresponding changes in bio-optical properties were tracked at one station (114.29°E, 22.06°N) located in the Pearl River estuary.

[Reflectance of sea ice in Liaodong Bay].

In the present study, the relationships between sea ice albedo and the bidirectional reflectance distribution in Liaodong Bay were investigated. The results indicate that: (1) sea ice albedo alpha(lambda) is closely related to the components of sea ice, the higher the particulate concentration in sea ice surface is, the lower the sea ice albedo alpha(lambda) is. On the contrary, the higher the bubble concentration in sea ice is, the higher sea ice albedo alpha(lambda) is.