Biomarkers prediction and immune landscape in ulcerative colitis: Findings based on bioinformatics and machine learning.

Background: Ulcerative colitis (UC) presents diagnostic and therapeutic difficulties. The primary objective of this study is to identify efficacious biomarkers for diagnosis and treatment, as well as acquire a deeper understanding of the immuneological characteristics associated with the disease.

Methods: Datasets relating to UC were obtained from GEO database.

The Threshold Effect of Swine Epidemics on the Pig Supply in China.

The pig industry is the pillar industry of animal husbandry in China, and epidemics can lead to drastic changes in pig supply, affecting the healthy development of the pig industry and residents' quality of life. This study analyzed the mechanism of the effect of swine epidemics on nonlinear shocks to pig supply, and monthly data on pig supply from January 2012 to June 2020 were applied to study the threshold effect of swine epidemics on pig stock and slaughter in China empirically, using the index of swine epidemics' width (ISEW) as the threshold variable. The results of this study were as follows: (1) The influence of the ISEW over 7 months on pig stock in China was divided into two ranges, and the pig stock did not change significantly when the ISEW was less than 0.