Publications by authors named "Guido Trezeguet Renatti"
Avoidance of steroids in pediatric liver transplantation may reduce toxicity and morbidity. The aim of this study was to analyze the feasibility of a steroid-free tacrolimus-basiliximab immunosuppression scheme, the risk factors associated with steroid requirement, and safety parameters. Patients who underwent liver transplantation for biliary atresia between 2011 and 2019 were included and followed for 6 months after transplantation.
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- A study aimed to understand how tacrolimus is absorbed in pediatric liver transplant patients who cannot take the medication orally, particularly focusing on those who are sedated or on mechanical ventilation.
- Researchers collected data from 26 children who underwent liver transplants and analyzed it using a sophisticated modeling software, revealing that tacrolimus behaves differently based on sedation status.
- The findings suggest that the model successfully describes the medication's absorption and could improve dosing strategies post-transplant once validated further.