Publications by authors named "Guido Spoto"
In this study, we designed squaraine-based dyes with a 2-amino pyrrole donor unit and acene groups like anthracene and pentacene. These dyes incorporate three different electron-withdrawing groups - cyanoacrylate (A1), phosphonate (A2) and boronic acid (A3) - as linkers to the TiO semiconductor. The spectroscopic, electronic and photochemical properties of these compounds were investigated using density functional theory (DFT) and time-dependent density functional theory (TDDFT) simulations.
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- A new point-of-care platform has been developed that combines reliability and user-friendliness for detecting phenylalanine in blood samples from patients with phenylketonuria (PKU).
- The system includes a mobile app for data collection and visualization, an electronic unit, and a disposable sensor that utilizes enzymatic recognition and gold nanostructure formation for accurate measurements.
- Clinical testing has shown that this "smart sensor" allows PKU patients to self-monitor their phenylalanine levels, enabling quick adjustments to their therapy and improving overall health management.