Publications by authors named "Guido Libondi"
Article Synopsis
- The study systematically reviewed and compared autologous breast reconstruction (ABR) and implant-based breast reconstruction (IBR) for breast cancer treatment, examining multiple databases for relevant studies.
- It found that patients generally reported higher aesthetic satisfaction and overall treatment satisfaction with ABR compared to IBR, although both procedures had similar safety profiles and complication rates.
- However, ABR was associated with significantly higher costs, highlighting the need for careful consideration of both methods' benefits and drawbacks in clinical decision-making.
Background: The transverse upper gracilis (TUG) flap is the senior authors' second choice for autologous breast reconstruction when the DIEP flap is not available. It provides durable, pliable tissue with well hidden scars. The main criticism of this flap is the limited volume, donor site complications, short pedicle and vessel mismatch depending on which recipient vessels are used.
View Article and Find Full Text PDFRecent research suggests that statins might be useful in the process of wound healing, playing a positive immune-modulatory role, improving microvascular function and reducing oxidative stress. The aim of this pilot study was to evaluate the efficacy of topic application of Simvastatin-based cream in the treatment of chronic vascular cutaneous ulcers, comparing this type of treatment to a collagen-based dressing, proven to be effective for ulcer treatment. A total of 20 ulcers were studied in 2 Groups of randomly-chosen patients for a period of one month.
View Article and Find Full Text PDFAdipose-derived stem cells are an ideal mesenchymal stem cell population for regenerative medical application. The isolation procedure is performed by mechanical isolation under a laminar air flow bench without using serum or animal-derived reagents; cells were characterized by flow cytometric analysis. Cell availability is improved compared with enzymatic digestion procedures.
View Article and Find Full Text PDFBackground: Human adult adipose tissue is an abundant source of mesenchymal stem cells (MSCs). Moreover, it is an easily accessible site producing a considerable amount of stem cells.
Methodology/principal Findings: In this study, we have selected and characterized stem cells within the stromal vascular fraction (SVF) of human adult adipose tissue with the aim of understanding their differentiation capabilities and performance.