Paleo-geomorphic features of pre-Jurassic and its oil-controlling effect in Wuqi-Dingbian area.

The Fuxian-Yan10 layers are the main oil-producing reservoirs of Jurassic in Wuqi-Dingbian area of Ordos Basin. However, due to the lack of understanding of the pattern and distribution characteristics of oil reservoirs, the benefits of exploration and development are restricted. In order to provide theoretical guidance for the study of similar geological features, based on the analysis of paleogeomorphic features and evolution, the analysis focuses on the influence of palaeo-geomorphology on oil reservoir distribution, and summarizes the main types of reservoir models in the study area.

Inhalation of diesel exhaust particulate matter accelerates weight gain via regulation of hypothalamic appetite-related genes and gut microbiota metabolism.

Mice exposed to diesel exhaust particulate matter (DEPM) exhibited accelerated weight gain. Several hypothalamic genes, hormones (serum Hypothalamic-Pituitary-Adrenal (HPA) axis hormones and gastrointestinal peptide tyrosine tyrosine (PYY)), metabolites (intrahepatic triglyceride (IHTG) and fecal short-chain fatty acids (SCFAs)), and gut microbiota structure, which may influence obesity and appetite regulation, were examined. The result suggested that DEPM-induced accelerated weight gain may be associated with increased expression of hypothalamic Gamma-aminobutyric acid (GABA) type B receptor, tight junction protein, and orexin receptors, in addition with decreased IHTG and repressed HPA axis.

Inhalation of diesel exhaust particulate matter induces locomotor hyperactivity and its relationship with brain and gut metabolism.

Diesel exhaust particulate matter (DEPM) are important components of urban air pollution worldwide. Recent studies proved that airborne DEPM can enter the human brain, which was associated with brain and mental diseases. In this study, we investigated the effects of DEPM exposure on behavior, and explored potential mechanisms from the perspective of metabolism in specific brain regions and short chain fatty acids (SCFAs) in the gut using mice.

An miRNA-mRNA integrative analysis in human placentas and mice: role of the Smad2/miR-155-5p axis in the development of fetal growth restriction.

Functional disorder of the placenta is the principal cause of fetal growth restriction (FGR), usually cured with suitable clinical treatment and good nursing. However, some FGR mothers still give birth to small for gestational age (SGA) babies after treatment. The ineffectiveness of treatment in such a group of patients confused physicians of obstetrics and gynecology.

Low Dose of Folic Acid Can Ameliorate Hyperhomocysteinemia-Induced Cardiac Fibrosis and Diastolic Dysfunction in Spontaneously Hypertensive Rats.

To evaluate whether lowering plasma homocysteine (Hcy) levels at different doses of folic acid (FA) could reduce cardiac fibrosis and diastolic dysfunction in spontaneously hypertensive rats (SHRs) with hyperhomocysteinemia (Hhcy) and investigate the possible mechanism of action.We randomly divided 32 male SHRs into control, Hhcy, Hhcy + low-dose FA (LFA), and Hhcy + high-dose FA (HFA) groups. Echocardiography and Masson staining of cardiac tissue were used to assess diastolic function and cardiac fibrosis.

Numerical simulation of electrohydrodynamics of a compound drop based on the ternary phase field method.

Analytical and numerical methods are often used to study the behavior of multiphase fluid under electric field. Compared with analytical methods, numerical methods can simulate the real physical phenomenon of multiphase fluid dynamics in a large deformation range. The finite element method is mainly applied in two-phase fluid currently, although it can be used to analyze the small and large deformation of multiphase fluid under electric field.

Far-Red Light-Induced Reversible Addition-Fragmentation Chain Transfer Polymerization Using a Man-Made Bacteriochlorin.

To overcome the challenge of photoregulated living radical polymerization in long-wavelength radiation, a photoinduced electron transfer reversible addition-fragmentation chain transfer (PET-RAFT) polymerization in far-red wavelength (λ = 740 nm) is reported by using a man-made bacteriochlorin as a photocatalyst. A reduced tetraphenylporphyrin (RTPP) having a natural bacteriochlorin macrocycle ring with two reduced pyrrole rings was synthesized with strong absorption in the far-red light region (700-765 nm) and applied for the PET-RAFT polymerization as a photoredox catalyst, which offered excellent control over molecular weight and polydispersities and oxygen tolerance for the polymerization of (methyl) acrylates monomers, and exhibited attractive features of "living" radical polymerization. Benefiting from high penetration of far-red light, the polymerization was also well-controlled when the reaction vessel was covered by translucent animal tissue barriers, for example, skin.

The correlation between IL-20 and the Th2 immune response in human asthma.

Backround: Interleukin-20 (IL-20) belongs to the IL-10 family, which has been shown to be crucial in immune responses, regulation of inflammatory responses, hemopoiesis, and epidermal cell and keratinocyte differentiation. However, the role of IL-20 in asthma remains unclear. Here, our aim is to evaluate the correlation between IL-20 and the Th2 immune response in human.

Interleukin-20 promotes airway remodeling in asthma.

Previous studies have demonstrated that interleukin-20 (IL-20) is a pro-inflammatory cytokine, and it has been implicated in psoriasis, lupus nephritis, rheumatoid arthritis, atherosclerosis, and ulcerative colitis. Little is known about the effects of IL-20 in airway remodeling in asthma. The aim of our study was to demonstrate the function of IL-20 in airway remodeling in asthma.