Six new compounds with neuroprotective activity from the leaves of Paeonia lactiflora Pall.

Twenty constituents, three new terpenes named Paeoniterpene A-C (1-3), and three new fatty glycosides named Paeoniglycoside A-C (4-6) were isolated from the leaves of Paeonia lactiflora Pall. The structures of compounds 1-6 were identified using extensive spectroscopic methods, such as NMR, MS, CD, IR, and UV. Compounds 4-6 were characterized through quantum chemical calculations and DP4 probability analysis, and ECD definitively confirmed their structures.

Three new compounds from the fruits of L. and their anti-inflammatory activities.

Three new compounds 1-glyceryl 9(), 10(), 11()-trihydroxy-12()-octadecenoate, 2'-20---hydroxyphenylpropionyloxy-20-hyd-roxyarachidic acid glycerol ester (), 3---l-arabinopyranosyl-(1→6)--d-glucopyranoside of ethyl (3)-hydroxybutanoate (), as well as a new natural product () were isolated from the fruits of L. The structures of 26 compounds were determined by comprehensive spectroscopic analyses, NMR calculation, chemical methods, and comparisons of spectroscopic data. Compounds and exhibited good anti-inflammatory activity in the LPS-induced RAW 264.

[Mechanism prediction of Simiao Yongan Decoction in treatment of psoriasis arthritis based on network pharmacology].

To explore the main target and signal pathway of Simiao Yongan Decoction in the treatment of psoriatic arthritis(PsA) by network pharmacology, so as to reveal the intervention mechanism of Simiao Yongan Decoction in the treatment of psoriatic arthritis. The platform of pharmacology technology of traditional Chinese medicine system(TCMSP) was used to predict and screen the active ingredients of Simiao Yongan Decoction, and GeneCards database was searched to obtain the disease target related to the psoriatic arthritis. Protein interaction network model was constructed with STRING platform; drug-component-target-disease network map was constructed with Cytoscape Software; Wayne Diagram of common target of Simiao Yongan Decoction and psoriasis arthritis was drawn with the help of ClusterProfiler R Software.

[Preparation instructions for Experts consensus statement on Cheezheng Xiaotong Tiegao in clinical practice].

As a topical plaster developed by modern pharmaceutical technology based on traditional Tibetan medicine,Cheezheng Xiaotong Tiegao has functions of promoting blood circulation,relieving swelling and relieving pain. Since its introduction in 1993,it has been widely used in the treatment of various types of acute and chronic musculoskeletal pain and various types of spinal,joint and soft tissue diseases. In order to better standardize the clinical application and improve the clinical efficacy of Cheezheng Xiaotong Tiegao,the research and development work of the Experts consensus statement on Cheezheng Xiaotong Tiegao in clinical practice was officially launched on October 19,2017,upon approval from China Association of Chinese Medicine.

[Introduction to Professor Ma Guiqin's experience in treatment of occupational pneumoconiosis].

Occupational pneumoconiosis refers to a group of occupational pulmonary diseases,which is mainly characterized by diffuse fibrosis of lung tissue caused by inhalation of different pathogenic productive dust and retention in the lungs during occupational activities for a long period of time. According to the classification and catalogue of occupational diseases in China,it is mainly classified into 12 categories,such as silicosis,coal worker's pneumoconiosis,asbestos lung. At present,it is the most serious and most common occupational disease in China.

[Evaluation of coronary artery diameter in normal children by echocardiography and its clinical significance].

Objective: To obtain normal range of coronary artery diameter with body surface area (BSA) dynamic changes in normal children at different age.

Method: The left main coronary artery (LCA), left anterior descending artery (LAD), left circumflex artery (LCX) and the right coronary artery (RCA) diameter were measured in 400 normal subjects from Chinese population aged 0 d to 18 years [(6.43 ± 4.

Congenital vascular rings: a rare cause of respiratory distress in infants and children.

Background: Congenital vascular rings may often cause unexplained respiratory symptoms in infants and young children. Their diagnosis and treatment are often delayed. Few studies of vascular rings have been reported in China.