[Relationship between D2-40-labeled lymphatic vessel invasion and lymph node metastasis of breast cancer].

Objective: To investigate the feasibility of D2-40 labeling for detecting lymphatic vessels in breast cancer tissues and the clinicopathological implications of lymphatic vessel invasion (LVI).

Methods: Immunohistochemistry was used to detect the expression of D2-40 and lymphatic invasion in 72 cases of breast cancer and 15 benign breast tumor tissues, and their correlations to the clinicopathological factors were analyzed.

Results: The positivity rate of LVI was 69.

[Expressions of D2-40 and CD34 in invasive ductal carcinoma of the breast and the clinical implications].

Objective: To investigate the expression of D2-40 and CD34 in invasive ductal carcinoma of the breast and the clinical significance.

Methods: D2-40 and CD34 expressions were detected immunohistochemically in 108 cases of invasive ductal carcinoma of the breast and 30 cases of breast fibroadenoma. The lymphatic microvessel density (LMD) and the microvessel density (MD), marked by D2-40 and CD34, respectively, were calculated and their relationship with the clinicopathological factors was analyzed.

[Relationship between micro-lymphatic vessel density and lymphatic metastasis in follicular thyroid carcinoma].

Aim: To investigate the relationship between micro-lymphatic vessel density (MLVD) and lymphatic metastasis in follicular thyroid carcinoma (FTC).

Methods: MLVD and micro-vascular density (MVD) were determined and counted by Envision immunohistochemistry using D2-40 and CD34 monoclonal antibodies in 35 specimens of follicular thyroid carcinoma(FTC)and 20 of nodular goiter. The relationship between MLVD and lymphatic metastasis was analyzed.