[Spatial Distribution, Source Analysis, and Risk Assessment of Multiple Antibiotics in Chaohu Lake Basin].

Chaohu Lake is the fifth largest freshwater lake in China that meets the needs of surrounding industries for water, tourism, and flood storage, making it important for the socio-economic development and modernization of Anhui Province. As an important ecological wetland in the lower reaches of the Yangtze River, many rare bird habitats are present along the coast of Chaohu Lake. Therefore, it is eco-economically important to study antibiotic pollution in Chaohu Lake.

[Hydrochemical and Stable Isotopic Characteristics and Transformation Relationship of Water Bodies in the Guohe River Basin, Anhui Province].

The Guohe River Basin in Anhui Province was selected as the research area for this study. By collecting surface water, shallow groundwater, and middle-deep groundwater samples, various hydrochemical parameters and stable isotopes of water in different water bodies were analyzed using methods such as the Gibbs diagram, ion ratios, and MixSIAR model to reveal and quantify the transformation relationships between these water bodies. The results indicated that both surface water and groundwater in the study area were predominantly neutral to weakly alkaline.

Spatial distribution characteristics and prediction of fluorine concentration in groundwater based on driving factors analysis.

Excess fluoride (F) in groundwater can be hazardous to human health. A total of 360 ground water samples was collected from northern Anhui, China, to study the levels, distribution, and source of F. And on this basis, predicting the spatial distribution of F in a wider scale space.

[Spatial Distribution and Pollution Assessment of Dissolved Heavy Metals in Chaohu Lake Basin During the Wet Season].

The spatial distribution characteristics of the mass concentration of V, Cr, Mn, Ni, Cu, Zn, Pb, Cd, Fe, and Sb in the Chaohu Lake basin and ten surrounding rivers during the wet season were explored. The results showed that the average mass concentration of heavy metals in the western and northwestern Chaohu Lake surrounding rivers was higher than that in the central and eastern regions. The correlation analysis showed a significant positive correlation between the concentrations of Cu, Ni, Zn, Pb, and Cd, which indicated a similarity of spatial distribution among the five elements.

[Elemental Composition Characteristics of PM and PM, and Heavy Pollution Analysis in Hefei].

Through the collection of atmospheric PM and PM samples in Hefei in 2018, combined with high-precision testing of elements in these samples, the elemental composition of PM and PM was studied during heavy pollution episodes and under non-pollution conditions. The main pollutant sources and causes of heavy pollution in Hefei are also discussed based on an analysis of the differences in the element composition of atmospheric particles. The results showed that, among the 16 elements detected, the mass concentrations of Si, Al, Mg, and Ca during heavy pollution episodes were lower than during non-polluted conditions.

Uptake, accumulation and phytoextraction efficiency of cesium in .

To evaluate the phytoextraction efficiency of from Cs-contaminated soils and analyze the mechanism of Cs accumulation in , we analyzed the characteristics of Cs bioaccumulation and subcellular distribution, in addition to its chemical forms in the plant under hydroponic conditions. The results showed that total Cs content in the aboveground parts and the entire plant were as high as 6137.32 mg·kgdry weight and 7338.

Effects of cesium accumulation on chlorophyll content and fluorescence of Brassica juncea L.

The aim of our study was to investigate the toxicological mechanism of cesium on Indian mustard (Brassica juncea L.). The impact of cesium toxicity to plants was evaluated using phytophysiology and genetic methods.

[Temporal-spatial Distribution and Pollution Assessment of Dissolved Heavy Metals in Chaohu Lake].

Surface water samples were collected in different seasons from Chaohu Lake to determine the concentrations and potential environmental impacts of nine dissolved heavy metals (As, Hg, Cd, Cu, Pb, Zn, Cr, Ni, and Co). The concentrations of the selected heavy metals were determined by inductively coupled plasma-optical emission spectrometry (ICP-OES, ICAP6000 series). The single pollution index method and integrated pollution index method were used to evaluate the potential environmental impacts.

[Spatial and Temporal Distributions of Nitrogen and Phosphate in the Chaohu Lake].

In order to determine the concentrations, spatial and temporal distributions of nitrogen ( N) and phosphorus (P) nutrients in Chaohu Lake, the surface water samples were collected systemically in different flood seasons by grid sampling methods. Meanwhile, the predominant pollution factors and priority control area were confirmed. The results showed that the concentrations of TP, TN and NO3- -N in the inflowing rivers were higher than the V class water standard, the concentrations of nutrients in wet season were lower than those in normal season and dry season in Nanfei River and Shiwuli River, while the levels of nutrients in the other selected rivers were higher in wet season.

Elevated glycated hemoglobin levels may increase the risk of atrial fibrillation in patients with diabetes mellitus.

Background: As the most common cardiac arrhythmia, atrial fibrillation (AF) is always accompanied with various complications if without detection and treatment timely. Blood-based pleiotropic molecule biomarkers have now been popularly applied in clinical detection. We hence performed this meta-analysis to evaluate the correlation of serum glycated hemoglobin (HbA1c) levels with the risk of AF in patients with diabetes mellitus (DM).

Prognostic role of PIK3CA mutations and their association with hormone receptor expression in breast cancer: a meta-analysis.

The phosphatidylinositol-4, 5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) gene is frequently mutated in breast cancer (BCa). Sex hormone receptors (HRs), including estrogen receptor (ER) and progesterone receptor (PR) play pivotal roles in BCa. In this study, we evaluated the association between PIK3CA mutations and ER/PR expression and the prognostic role of PIK3CA mutations in BCa patients, and in particular, HR-positive BCa.

A single nucleotide polymorphism in PIK3CA gene is inversely associated with P53 protein expression in breast cancer.

Single nucleotide polymorphism (SNP) rs17849071 was recently reported to be inversely associated with PIK3CA amplification in follicular thyroid cancer, but the main function of this SNP remains unclear. In this study, by using PCR and sequencing method, we explored whether this SNP was associated with P53 expression status and other clinicopathological characteristics in 62 Chinese breast cancer (BCa) patients. In our results, P53 protein accumulation was significantly associated with HER2 overexpression (P = 0.

[The spectrum studies of structure characteristics in magma contact metamorphic coal].

The structural parameters evolution of coal due to the influence of intrusions of hot magma was investigated and analyzed. X-ray diffraction and laser confocal microscope Raman spectroscopy were used to test and analyze 4 coal samples undergoing varying contact-metamorphism by igneous magmas in borehole No. 13-4 of Zhuji coal mine, Huainan coalfield.

Synthesis and antitumor activity of a series of osmium(VI) nitrido complexes bearing quinolinolato ligands.

A series of osmium(VI) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that Os(VI)≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

Identification of nitrate sources in Taihu Lake and its major inflow rivers in China, using δ(15)N-NO(3)(-) and δ(18)O-NO(3)(-) values.

In the present study, δ(15)N and δ(18)O-NO(3)(-) values, as well as concentrations of some major ion tracers were determined in seasonal water samples from Taihu Lake and major watersheds to investigate the temporal and spatial variations of nitrate sources and assess the underlying nitrogen (N) biogeochemistry process. The results lead to the conclusion that the nitrate concentrations in Taihu Lake are lower in summer than that in winter due to the dilution effect of wet deposition. In winter, sewage and manure were the primary nitrate sources in major inflow rivers and North Taihu Lake (NTL), while nitrate sources in East Taihu Lake (ETL) probably derived from soil organic N.

Fecal steroids in riverine runoff of the Pearl River Delta, South China: levels, potential sources and inputs to the coastal ocean.

Domestic sewage is a potential source of contamination deteriorating water quality in rivers and coastal environments. The present study determined the concentrations of eight steroids in both filtrate and suspended particulate matter (SPM) samples collected monthly at the eight major riverine runoff outlets of the Pearl River Delta (PRD), South China, from March 2005 to February 2006. The concentration of the eight steroids (sum of which is defined as Sigma(8)steroid) in the filtrate and SPM samples ranged 16.

Serum proteomes of hypertension patients with abundant phlegm-dampness.

Objective: To study the serum proteomes of essential hypertension (EH) patients with abundant phlegm-dampness, and try to find special proteins associated with abundant phlegm-dampness syndrome.

Methods: Fifty-nine hypertension patients were included, and the patients were divided into abundant phlegm-dampness syndrome group (39 cases) and non-phlegm-dampness syndrome group (20 cases). To find the special proteins associated with abundant phlegm-dampness, the EH patients with non-phlegm-dampness and another 30 healthy persons were regarded as control.

Some potential hazardous trace elements contamination and their ecological risk in sediments of western Chaohu Lake, China.

The Chaohu is one of the largest five freshwater lakes in China. It provides freshwater for agriculture, life, and part of industry. The quality of water becomes worst and worst due to the toxic matter.

Development of a high sensitivity, nested Q-PCR assay for mouse and human aromatase.

Measurement of breast tissue estradiol levels could provide a powerful method to predict the risk of developing breast cancer but obtaining sufficient amounts of tissue from women is difficult from a practical standpoint. Assessment of aromatase in ductal lavage fluid or fine needle aspirates from breast might provide a surrogate marker for tissue estrogen levels but highly sensitive methods would be required. These considerations prompted us to develop an ultra-sensitive, "nested" PCR assay for aromatase which is up to one million fold more sensitive than standard PCR methods.

[Analysis of antimicrobial resistance of clinical isolates of enterococci from Beijing and other areas in China].

Objective: To analyze the antimicrobial resistance of enterococci in Beijing and other areas in China.

Methods: Disk diffusion method was used to test the antimicrobial resistance of 1978 enterococcal isolates from 4 teaching hospitals in Beijing and 53 grade 3 A hospitals in other areas of China The laboratory data were analyzed by WHONET5 statistic software.

Results: Enterococcus.