[Identification of B(A) Blood Group Serology Combined with Molecular Biology and Blood Transfusion Strategy].

Objective: To analyze the reasons for ABO blood group forward typing and reverse typing incompatibility of the proband by serological and molecular biological tests, so as to clarify the blood group and genetic rules and determine the reasonable transfusion strategy.

Methods: On the basis of serological testing results, PCR-SSP method was utilized for the ABO exon sequencing in the peripheral blood of the proband and 5 family members, and blood group results were comprehensively analyzed.

Results: The serological results of ABO blood group of the proband were incompatibility, and the molecular biological test results showed that there was a mutation compared with , which was consistent with subtype, and the genotype was .

Chinese Consensus Report on Family-Based Infection Control and Management (2021 Edition).

Objective: infection is mostly a family-based infectious disease. To facilitate its prevention and management, a national consensus meeting was held to review current evidence and propose strategies for population-wide and family-based infection control and management to reduce the related disease burden.

Methods: Fifty-seven experts from 41 major universities and institutions in 20 provinces/regions of mainland China were invited to review evidence and modify statements using Delphi process and grading of recommendations assessment, development and evaluation system.

Clinical value of serum cancer antigen 19-9 as a tumor screening marker among healthy individuals.

Purpose: To investigate the clinical value of serum cancer antigen 19-9 (CA 19-9) as a tumor screening marker among healthy individuals.

Methods: CA 19-9 levels were measured in 1921 healthy individuals and were compared to reference values. Analysis based on gender was also carried out.

Upregulation of microRNA 181c expression in gastric cancer tissues and plasma.

Objective: To test the microRNA-181c (miR-181c) expression in tissues and plasma of gastric cancer (GC) cases, analyze any correlations, and explore the possibility of miR-181c as a potential molecular marker for GC diagnosis.

Materials And Methods: Relative miR-181c expression levels in cancers and plasma from 30 GC patients was tested using reverse transcription?real-time fluorescent quantitation PCR and compared to that in samples from 30 gastric ulcer and 30 chronic gastritis patients.

Results: The miR-181c expression level in the GC tissues was significantly higher than that in the gastric ulcer and chronic gastritis tissues (P = 0.

[Expression of peroxiredoxin 6 in gastric cancer and its clinical significance].

Objective: To elucidate the significance of anti-oxidant protein peroxiredoxin 6 (Prx6) expression in gastric cancer (GC) tissue.

Methods: Eighty-six GC tissues and 69 para-cancer tissues from surgically resected specimens were included. And the clinico-pathological data were collected by reviewing medical records.

[Ilaprazole based bismuth-containing quadruple regimen for the first-line treatment of Helicobacter pylori infection: a multicenter, randomized, controlled clinical study].

Objective: To explore the effects of 7-day quadruple regimen as the first-line therapy strategy for Helicobacter pylori(H. pylori)infection and compare the eradication rate of ilaprazole versus esoprazole-based regimen.

Methods: A total of 440 patients with H.

[Jinghuaweikang capsules combined with triple therapy in the treatment of Helicobacter pylori associated gastritis and duodenal ulcer and analysis of antibiotic resistance: a multicenter, randomized, controlled, clinical study].

Objective: To explore the efficacy of Jinghuaweikang capsules plus triple therapy (LACJ) in treatment of Helicobacter pylori (H. pylori) associated gastritis or duodenal ulcer, compare it with bismuth-containing quadruple therapy (LACB) and standard triple therapy (LAC) and analyze the antibiotic sensitivity of gastric mucosal H. pylori strains from the failed patients.

Di-μ-sulfato-κO:O'-bis-{bis-[3-(2-pyrid-yl)pyrazole]cobalt(II)}.

In the centrosymmetric binuclear title molecule, [Co(2)(SO(4))(2)(C(8)H(7)N(3))(4)], the Co(II) ion is coordinated by two N,N'-bidentate 3-(2-pyrid-yl)pyrazole ligands and two sulfate ions, generating a distorted cis-CoO(2)N(4) octa-hedral geometry for the metal atom. The dihedral angles between the pyridine and pyrazole rings in the two ligands are 10.5 (2) and 7.

Diazido-bis{2-[3-(dimethyl-amino)propyl-imino-meth-yl]phenol}manganese(III) perchlorate.

The title compound, [Mn(N(3))(2)(C(12)H(18)N(2)O)(2)]ClO(4), was synthesized from manganese(III) acetate, sodium azide and 2-[3-(dimethyl-amino)propyl-imino-meth-yl]phenol by a hydro-thermal reaction. The Mn(III) ion is hexa-coordinated by two N and two O atoms from two phenolate ligands and two N atoms from two azide ligands. The Mn(III) cation lies on an inversion centre and, as a result, the asymmetric unit comprises one half-mol-ecule.

Diaqua-1κO,3κO-di-μ-cyanido-1:2κN:C;2:3κC:N-dicyanido-2κN-bis-{4,4'-dibromo-2,2'-[propane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}-1κO,N,N',O';3κO,N,N',O'-1,3-dimanganese(III)-2-nickel(II).

In the title compound, [Mn(2)Ni(C(17)H(14)Br(2)N(2)O(2))(2)(CN)(4)(H(2)O)(2)] or [{Mn(C(17)H(14)Br(2)N(2)O(2))(H(2)O)}(2)(μ-CN)(2){Ni(CN)(2)}], each Mn(III) atom is chelated by a Schiff base ligand via two N and two O atoms and is additionally coordinated by a water mol-ecule to give a slightly distorted octa-hedral geometry. Two such Mn(III) ions are linked by a square-planar Ni(CN)(4) unit, which lies on an inversion centre. A two-dimensional network is formed by O-H⋯O and O-H⋯N hydrogen bonds.

[Preventive effects of teprenone on gastric mucosal lesions induced by Helicobacter pylori in mice].

Objective: To determine the preventive effect of teprenone on gastric mucosal injury induced with Helicobacter pylori concentrated culture supernatant (CCS) in Balb/c mice.

Methods: Gastric mucosa lesions were induced with intragastrical administration of Helicobacter pylori CCS. Sixty Balb/c mice were divided into control group, injury group, sucralfate protective group and teprenone protective group.

[Proliferative changes of human gastric mucosa cells in different pathological lesions and their clinical significance].

Objective: To investigate the variation of cell proliferation and growth in different pathological lesions of gastric mucosa and to assess the possible roles of expression of epidermal growth factor receptor (EGFR), transforming growth factor beta receptor type I and type II (TGF(beta)RI, TGF(beta)RII).

Methods: The proliferating cell nuclear antigen (PCNA), EGFR, TGF(beta)RIand TGF(beta)RII were studied in chronic superficial gastritis (CSG, n = 30), chronic atrophic gastritis (CAG, n = 26), intestinal metaplasia (IM,n = 40), Dysplasia (DYS, n = 22), early gastric cancer (EGC, n = 22), advanced gastric cancer (AGC, n = 26) by immunohistochemical methods and their relations with carcinogenesis were analyzed.

Results: (1) In different gastric mucosa lesions (CSG, CAG, IM, DYS, EGC, AGC), there were significantly different expression of PCNA (chi2 = 91.

[Effect of helicobacter pylori on gastric mucosal cell proliferation in gastritis].

Objective: To study the effect of helicobacter pylori on gastric mucosal cell proliferation in gastritis.

Methods: Fifty-six gastritis patients with or without Helicobacter pylori infection (Hp+ 27; Hp- 29) were selected. The expression of proliferation cell nuclear antigen (PCNA), epidermal growth factor receptor (EGFR), transforming growth factor beta receptor type I and type II(TGFbetaRI, TGFbetaRII) in gastric mucosa were examined by immunohistochemical method.

[The relation between Helicobacter pylori infection and p53 mutation, MG-7 antigen and AgNORs expression in the development of gastric mucosa lesions].

Objective: To explore the relation between H. pylori infection and the development of gastric mucosa lesions, and to evaluate the effect of H. pylori infection on cell proliferation, p53 mutation, and MG-7 antigen expression in patients with gastric precancerous lesions.