Publications by authors named "Gui-Yuan Liu"

A kind of plasmonic nanostructure is proposed that can generate the arbitrary superposition of orbital angular momentum (OAM) states in surface plasmons (SPs), which is achieved by combining the segmented spirals with nanoslit pairs. The structures can independently modulate both the phase and amplitude of SP waves, and thus enable the superposition of two OAM states with arbitrary topological charges (TCs) as well as free control of their relative amplitudes. Superposed states distributed over the entire Bloch sphere and hybrid superposed states with different TCs were constructed and experimentally demonstrated.

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Article Synopsis
  • MiR-130a-3p shows anti-tumor effects across various cancers and may specifically inhibit the Wnt signaling pathway, which is crucial in tumor development.
  • Both colorectal cancer (CRC) tissues and cell lines exhibited lower levels of miR-130a-3p compared to normal controls, indicating its potential role in CRC progression.
  • Overexpression of miR-130a-3p reduced CRC cell growth and downregulated WNT1 and its downstream factors, with WNT1 acting as a direct target of miR-130a-3p; thus, both could be promising targets for CRC treatment.
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A new lanostane triterpenoid () and two known (, ) analogues were isolated from . Their chemical structures were identified by spectral data including HR-ESI-MS, 1 D, and 2 D NMR. These lanostane triterpenoids showed no cytotoxic activities against three human tumour cell lines (A172, SHSY5Y, and Hela), but exhibited the activity of promoting the gastrointestinal motility of zebrafish treated with Nile red.

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Five previously undescribed compounds, including two dendrobine-type alkaloids (1 and 2), three bibenzyl derivatives (3-5), along with six known compounds were isolated from orchids Dendrobium findlayanum. The structures and absolute configurations of the undescribed compounds were elucidated on the basis of HR-ESIMS, NMR spectroscopy, optical rotation value, as well as electronic circular dichroism (ECD) calculations. The cytotoxic effects of the isolated compounds on three human tumour cell lines (A172, SHSY5Y, and Hela) were evaluated by the MTT assay.

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Background: Gap junction beta-4 protein (GJB4), or connexin 30.3, a member of integral membrane proteins, has been shown to involve and may function as a tumor promoter in tumorigenesis. However, the role of GJB4 in gastric cancer (GC) is still unclear.

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A new triphenanthrene compound named 2,2',2'',7,7',7''-hexahydroxy-4,4',4''-trimethoxy-[9,9',9'',10,10',10'']-hexahydro-1,8,1',6''-triphenanthrene (), together with eleven known compounds (-), were isolated from tubers of . Their structures were determined by analysis of spectroscopic data.

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