Publications by authors named "Gui-Xin Wu"
Mangrove-derived actinomycetes are prolific chemical sources of complex and novel natural products, providing an excellent chance for new drug discovery. The chemical investigation of the mangrove-derived Streptomyces sundarbansensis 06037, led to the discovery of two previously undescribed enone fatty acids (1-2), one new phenylpropionate derivate (3), along with the isolation of the ten known components (4-13). Those chemical structures of isolates were elucidated on the basis of the analysis of diverse spectroscopic data.
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- The study aimed to compare clinical characteristics and outcomes of hypertrophic cardiomyopathy (HCM) patients with and without hypertension (HT) among 696 participants confirmed by genetic testing.
- HCM patients without HT were generally younger and exhibited distinct health metrics, including lower body mass index and smaller left ventricular dimensions, but faced higher risks of cardiovascular and all-cause death, especially in the non-surgical group.
- The findings suggest that the greater mortality in HCM patients without HT may be linked to differences in medical treatment, as those with HT received more active therapies.