Publications by authors named "Gui-Xian Yang"
Article Synopsis
- A new method for using light to convert α-fluoroacrylic acids into difluoroalkylated and polyfluoroalkylated compounds has been developed.
- This approach is versatile, allowing the use of various starting materials and producing specific monofluoroalkenes with a desirable structure under mild conditions.
- The technique works well with different functional groups, making it useful for modifying complex biological molecules.
Herein, a practical and efficient method for synthesizing monofluoroalkenyl phosphine oxides via photoinduced decarboxylative/dehydrogenative coupling of α-fluoroacrylic acids with phosphine oxides and phosphonates has been developed. Various α-fluoroacrylic acids and P(O)H compounds containing relevant functional groups, including tetrafluorobenzene and pentafluorobenzene, were converted into corresponding products with excellent -stereoselectivity in satisfactory yields. This method can be extended to achieve the synthesis of monofluoroalkenyl silanes under similar conditions.
View Article and Find Full Text PDF[Therapeutic effects of umbilical cord mesenchymal stem cells transplantation on systemic lupus erythematosus].
Sichuan Da Xue Xue Bao Yi Xue Ban
March 2014
Objective: To observe the efficacy of umbilical cord mesenchymal stem cells (UC-MSCs) transplantation for the patients with refractory systemic lupus erythematosus (SLE).
Methods: Thirty seven patients with SLE were enrolled in this study, and divided into conventional treatment group (control group, n = 20) and UC-MSCS adjuvant treatment group (treatment group, n= 17). All the patients in both two groups were treated with glucocorticoids and cyclophosphamide (CTX).